Actively Recruiting

Age: 18Years - 99Years
MALE
NCT07322627

ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients

Led by National Taiwan University Hospital · Updated on 2026-01-07

700

Participants Needed

1

Research Sites

98 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Alcohol consumption, smoking, and betel nut chewing have been proven to be closely associated with the risk of esophageal cancer (EC). Recent studies have shown that alcohol-related detoxification genes in the ALDH family influence individual susceptibility to esophageal cancer. Aldehyde dehydrogenase 2 (ALDH2) is one of the most important enzymes in the ALDH family, involved in the metabolism of alcohol, acetaldehyde, and environmental aldehydes in the human body. We hypothesize that functional variations in ALDH2 may have a significant impact on the survival of esophageal cancer patients. This study aims to investigate the correlation between ALDH2 gene polymorphism and the survival of esophageal cancer patients.

CONDITIONS

Official Title

ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients

Who Can Participate

Age: 18Years - 99Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who have been pathologically confirmed to have esophageal cancer
  • Patients who have signed consent forms to provide remaining samples for research
Not Eligible

You will not qualify if you...

  • Female patients
  • Patients younger than 18 years old

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

J

Jang-Ming Lee

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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