Actively Recruiting

Phase Not Applicable
Age: 18Years - 110Years
All Genders
NCT06232551

Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism

Led by Scott C. Woller, MD · Updated on 2024-07-17

152000

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

Sponsors

S

Scott C. Woller, MD

Lead Sponsor

J

Janssen Pharmaceuticals

Collaborating Sponsor

AI-Summary

What this Trial Is About

A new algorithm derived from only patient age and components of the complete blood count and basic metabolic panel can identify patients discharged from the hospital who may benefit from a blood thinner (called rivaroxaban) to decrease their risk of blood clots, and for whom the risk of bleeding is minimal. The purpose of this study is to evaluate the use of a pop-up alert, which will be seen by clinicians when a discharging patient has been identified as being someone for whom the risk of blood clots is high, but for whom bleeding risk is estimated to be low. The pop-up alert will be enabled in a sequential fashion for each group of hospitals in 1 month blocks. We will look to see if the pop-up alert changes the number of patients who receive rivaroxaban. We will also measure the outcomes of blood clots and bleeding among all discharging patients.

CONDITIONS

Official Title

Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism

Who Can Participate

Age: 18Years - 110Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Discharging clinician must be a physician, nurse practitioner, or physician assistant in hospitalist, internal medicine, or family medicine roles
  • Patient age 18 years or older
  • The patient encounter must be an inpatient stay
  • A signed hospital discharge order must be present
  • Patient must meet criteria for increased venous thromboembolism risk and low bleeding risk
Not Eligible

You will not qualify if you...

  • Patient is pregnant during the hospital encounter
  • Discharge order completed by clinician not in eligible roles
  • Patient is actively prescribed and intended to be discharged on anticoagulant medications including apixaban, dabigatran, dalteparin, enoxaparin, edoxaban, betrixaban, fondaparinux, rivaroxaban, or warfarin
  • Estimated creatinine clearance is less than 30 milliliters per minute based on the last available serum creatinine value

AI-Screening

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Trial Site Locations

Total: 1 location

1

Intermountain Medical Center

Murray, Utah, United States, 84107

Actively Recruiting

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Research Team

V

Valerie Aston, MBA

CONTACT

C

Carlos Barbagelata, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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