Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05437237

Algorithm Development Through AI for the Triage of Stroke Patients in the Ambulance With EEG

Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2022-06-29

1192

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Endovascular thrombectomy (EVT) enormously improves the prognosis of patients with large vessel occlusion (LVO) stroke, but its effect is highly time-dependent. Direct presentation of patients with an LVO stroke to an EVT-capable hospital reduces onset-to-treatment time by 40-115 minutes and thereby improves clinical outcome. Electroencephalography (EEG) may be a suitable prehospital stroke triage instrument for identifying LVO stroke, as differences have been found between EEG recordings of patients with an LVO stroke and those of suspected acute ischemic stroke patients with a smaller or no vessel occlusion. The investigators expect EEG can be performed in less than five minutes in the prehospital setting using a dry electrode EEG cap. An automatic LVO-detection algorithm will be the key to reliable, simple and fast interpretation of EEG recordings by ambulance paramedics. The primary objective of this study is to develop one or more novel AI-based algorithms (the AI-STROKE algorithms) with optimal diagnostic accuracy for identification of LVO stroke in patients with a suspected acute ischemic stroke in the prehospital setting, based on ambulant EEG data.

CONDITIONS

Official Title

Algorithm Development Through AI for the Triage of Stroke Patients in the Ambulance With EEG

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suspected acute ischemic stroke or known large vessel occlusion stroke as assessed by ambulance paramedic
  • Symptoms started or last seen well less than 24 hours before EEG acquisition
  • Age 18 years or older
  • Written informed consent by patient or legal representative (deferred)
Not Eligible

You will not qualify if you...

  • Skin defect or active infection on the scalp where the EEG cap is placed
  • Suspected or confirmed COVID-19 infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Amsterdam University Medical Centers, location AMC

Amsterdam, North Holland, Netherlands, 1105AZ

Actively Recruiting

Loading map...

Research Team

M

Maritta N van Stigt, MSc

CONTACT

J

Jonathan M Coutinho, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here