Actively Recruiting

Phase Not Applicable
Age: 5Years - 17Years
All Genders
NCT04331353

The Allergen Reduction and Child Health Study (ARCHS)

Led by Tulane University · Updated on 2025-09-09

290

Participants Needed

1

Research Sites

389 weeks

Total Duration

On this page

Sponsors

T

Tulane University

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Allergen Reduction and Child Health Study (ARCHS) is a 12-month, two group randomized control trial of children with asthma and who are exposed to cockroaches. Children ages 5 - 17 living in the Greater New Orleans area will be recruited from a variety of clinic and community settings. The overall goal of the study is to improve patient-centered asthma outcomes (asthma symptom days, health care utilization, asthma control and quality of life) by targeting one key allergen - cockroach exposure in the child's home. The investigators propose a simple intervention of insecticidal bait that is low cost, simple to implement, and which is lower toxicity than other forms of pest control. The reduction in the number of cockroaches in the home is an environmental outcome that is patient-centered and is likely to add to its acceptance by families of children with asthma.

CONDITIONS

Official Title

The Allergen Reduction and Child Health Study (ARCHS)

Who Can Participate

Age: 5Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 5 to 17 years
  • Uncontrolled persistent asthma defined by at least one of: overnight hospitalization for asthma in past 6 months OR two unscheduled clinic or emergency visits for asthma in past 12 months
  • On long term controller medication for asthma OR asthma symptoms 3 or more days per week over past 2 weeks OR nighttime asthma symptoms at least 3 times in past month
  • Exposure to cockroach indicated by trapping at least one cockroach in 3 days OR visual evidence by study staff
  • Child sleeps in target home at least 4 nights per week on average
  • Caregiver able to speak English or Spanish
Not Eligible

You will not qualify if you...

  • Other serious medical or chronic illnesses including chronic respiratory infections requiring daily medication
  • Cardiovascular disease requiring daily medication (excluding hypertension)
  • Taking a beta-blocker
  • Current active smoker
  • Currently receiving immunotherapy
  • Plans to move within the 12 month follow-up period

AI-Screening

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Trial Site Locations

Total: 1 location

1

Tulane University

New Orleans, Louisiana, United States, 70112

Actively Recruiting

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Research Team

D

Derek Werthmann, PhD

CONTACT

J

Joanna Baisier

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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The Allergen Reduction and Child Health Study (ARCHS) | DecenTrialz