Actively Recruiting
Allergy and Immunology Natural History Study
Led by Columbia University · Updated on 2026-02-04
10000
Participants Needed
1
Research Sites
859 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This protocol is a natural history study designed to evaluate subjects (and some family members) with suspected or identified genetic diseases of allergic inflammation or Immune Dysregulation. Patients determined by clinical history and outside evaluations to be of interest will be consented and enrolled into this study. Blood specimens, stored blood products and derivatives, saliva, hair, fingernail clippings, cord blood, umbilical cord, bone marrow, tissue biopsies and/or buccal swabs from such patients and/or their family members will be obtained for research studies related to understanding genetic and immunopathogenic bases of these diseases. Outside medical records may be obtained, and patient evaluations may be performed to correlate to research laboratory testing results.
CONDITIONS
Official Title
Allergy and Immunology Natural History Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects from birth to 99 years old with known or suspected inherited disorders of allergic inflammation, mast cell homeostasis, activation, or immune dysregulation
- Blood relatives of enrolled subjects are eligible
- No restrictions based on age, gender, race, or disability
- Willingness and ability to give informed consent
- Agreement to have blood stored for future immune system studies and other medical conditions
You will not qualify if you...
- Presence of acquired immune system abnormalities such as from cytotoxic chemotherapy or malignancy, if deemed by the investigator to interfere with evaluation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Columbia University Irving Medical Center / NewYork-Presbyterian Hospital
New York, New York, United States, 10032
Actively Recruiting
Research Team
J
Joshua D. Milner, MD
CONTACT
Y
Yannett Franklin
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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