Actively Recruiting
Allogeneic Use of Expanded Mesenchymal Stem Cells Derived From Adipose Tissue (HC106), Female Urinary Incontinence Women Over 50 Years Old
Led by Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz · Updated on 2025-05-01
60
Participants Needed
6
Research Sites
50 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Evaluate the feasibility and safety, obtaining initial efficacy data, of expanded allogeneic mesenchymal stem cells derived from adipose tissue (HC106) for the treatment of urinary incontinence in women over 50 years of age.
CONDITIONS
Official Title
Allogeneic Use of Expanded Mesenchymal Stem Cells Derived From Adipose Tissue (HC106), Female Urinary Incontinence Women Over 50 Years Old
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women over 50 years old
- Clinical diagnosis of genuine or mixed stress urinary incontinence lasting at least 6 months
- Predominance of stress-related urine loss when more than 50% of daily losses occur after exertion
- Failure or refusal of rehabilitative or surgical treatment
- No active urinary tract infection confirmed by negative urine culture at recruitment
- Signed informed consent form
You will not qualify if you...
- Previous surgery for incontinence, prolapse, or urological/gynecological/colorectal surgery
- Major surgery or serious trauma within the last 6 months
- Mixed urinary incontinence with predominant urgency symptoms
- History of high-pressure detrusor overactivity
- Presence of infravesical obstruction, vesico-ureteral reflux, or urinary fistula
- Any malignant neoplasm except basal or squamous cell skin carcinoma, or malignant tumors not in remission for at least 5 years
- Unstable or serious cardiopulmonary disease
- Medical or psychiatric illness deemed exclusionary by the researcher
- History of alcohol or substance abuse in the 6 months prior to inclusion
- Allergy to anesthetics
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Hospital Universitario del Henares
Coslada, Madrid, Spain, 28822
Actively Recruiting
2
Fundación Jiménez Díaz
Madrid, Madrid, Spain, 28040
Actively Recruiting
3
Hospital Universitario Doce de Octubre
Madrid, Madrid, Spain, 28041
Actively Recruiting
4
Hospital Universitario Rey Juan Carlos
Móstoles, Madrid, Spain, 28933
Actively Recruiting
5
Hospital Universitario Infanta Elena
Valdemoro, Madrid, Spain, 28342
Active, Not Recruiting
6
Hospital Universitario General de Villalba.
Villalba, Madrid, Spain, 28400
Actively Recruiting
Research Team
C
Carmen González Enguita, PhD
CONTACT
M
Mariano García Arranz, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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