Actively Recruiting
Alpha-Blockers Prior to Ureteral Access Sheath Placement in Flexible Ureteroscopy: A Randomized Prospective Study
Led by Pedro de Figueiredo Buchalla · Updated on 2025-08-15
140
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate whether the use of alpha-blockers before flexible ureterorenolithotripsy facilitates the passage of the ureteral access sheath. The trial will enroll adult patients diagnosed with kidney stones who are scheduled for flexible ureteroscopy. Participants will be randomly assigned to receive or not receive alpha-blockers for seven days before surgery. The primary outcome is the rate of successful sheath placement without the need for a second procedure. Secondary outcomes include the incidence of ureteral injuries and the need for additional surgical interventions. The goal is to improve surgical efficiency and patient outcomes in the treatment of kidney stones.
CONDITIONS
Official Title
Alpha-Blockers Prior to Ureteral Access Sheath Placement in Flexible Ureteroscopy: A Randomized Prospective Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years
- Diagnosed with nephrolithiasis requiring flexible ureterorenolithotripsy surgery
- Able to provide written informed consent
You will not qualify if you...
- Age < 18 years
- Pregnancy
- History of ureteral stricture, prior ureteral reconstructive surgery, or abdominal/pelvic radiotherapy
- Prior ureteroscopy or ipsilateral double-J stent placement within the past 3 months
- Chronic use of alpha-blockers for benign prostatic hyperplasia or medical expulsive therapy for ureteral stones
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centro Universitário FMABC
Santo André, São Paulo, Brazil, 09060-870
Actively Recruiting
Research Team
P
Pedro FB Buchalla, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NA
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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