Actively Recruiting

Age: 55Years - 75Years
All Genders
NCT05740683

Alpha-synuclein Rt-quic and Neurologic Symptoms in Persons With idiOpathic anosMiA

Led by Danish Dementia Research Centre · Updated on 2024-10-02

100

Participants Needed

2

Research Sites

513 weeks

Total Duration

On this page

Sponsors

D

Danish Dementia Research Centre

Lead Sponsor

D

Danish Reference Center for Prion Diseases, Rigshospitalet

Collaborating Sponsor

AI-Summary

What this Trial Is About

Test of early warning signs and RT-QuIC in patients with idiopathic olfactory dysfunction

CONDITIONS

Official Title

Alpha-synuclein Rt-quic and Neurologic Symptoms in Persons With idiOpathic anosMiA

Who Can Participate

Age: 55Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 55 to 75 years
  • Slowly progressing and non-fluctuating idiopathic olfactory dysfunction (iOD)
  • Able to give informed consent and cooperate as evaluated by the principal investigator
  • For controls: Age 55 to 75 years
  • For controls: Able to give informed consent and cooperate as evaluated by the principal investigator
Not Eligible

You will not qualify if you...

  • Diagnosed with neurodegenerative disease, dementia, Parkinson's disease, or major neurological/psychiatric condition
  • Anosmia or hyposmia caused by sino-nasal disease including chronic rhinitis and allergy
  • Olfactory dysfunction resulting from trauma, infection, congenital causes, surgery, toxins, or drugs affecting smell
  • Olfactory dysfunction that responds to systemic or local corticosteroids if tried
  • Severe nasal cavity abnormalities or infections
  • Overt signs of dementia or Parkinson's disease
  • Current alcohol or drug abuse
  • Terminal illness

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Danish Dementia Research Centre

Copenhagen, Denmark, 2100

Actively Recruiting

2

Oskar McWilliam

Copenhagen, Denmark, 2100

Actively Recruiting

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Research Team

O

Oskar McWilliam

CONTACT

K

Kristian S Frederiksen

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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