Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05632497

Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-11-24

120

Participants Needed

1

Research Sites

123 weeks

Total Duration

On this page

Sponsors

A

Assistance Publique - Hôpitaux de Paris

Lead Sponsor

F

Fondation de France

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment symbiosis and the mechanism (dysbiosis of intestinal microbiota, increase of intestinal permeability, immunity alteration and low-grade inflammation).

CONDITIONS

Official Title

Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged 18 years or older
  • Diagnosis of anorexia nervosa according to DSM-5 and CIDI
  • Body mass index (BMI) less than 15
  • Hospitalized for nutrition rehabilitation
  • Covered by health insurance
  • Signed informed consent form
  • For healthy volunteers: aged 18 years or older
  • For healthy volunteers: body mass index between 18.5 and 25
  • For healthy volunteers: covered by health insurance
  • For healthy volunteers: signed informed consent form
Not Eligible

You will not qualify if you...

  • Patients not meeting all DSM-5 or CIDI criteria
  • Antibiotic treatment within 2 months or laxative use within 3 weeks before hospitalization
  • Somatic diseases affecting intestinal microbiota such as Crohn's disease, diabetes, or chronic inflammatory diseases
  • Patients under guardianship
  • Patients covered by the French AME health scheme
  • Healthy volunteers with diseases affecting intestinal microbiota
  • Recent weight changes in healthy volunteers
  • Healthy volunteers under guardianship
  • Healthy volunteers covered by the French AME health scheme

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service de Nutrition Clinique, Hôpital Paul Brousse (APHP)

Villejuif, France, 94800

Actively Recruiting

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Research Team

M

Mouna HANACHI GUIDOUM, MD

CONTACT

J

Joël DORE

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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