Actively Recruiting
Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting
Led by University of Minnesota · Updated on 2026-03-19
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effects of a one-week alternate nostril breathing (ANB) exercise on the severity of nausea and vomiting in pregnant individuals during their first trimester. The study involves a prospective, two-arm, non-blinded randomized controlled design to compare this breathing practice against usual care. It focuses on pregnant participants experiencing mild to moderate nausea and vomiting during early pregnancy. Participants in the intervention group will learn the ANB technique through a brief orientation, followed by written and video instructions. They will perform ANB three times daily for 5 to 10 minutes over seven days, starting the day after enrollment. The control group will continue with usual care without the breathing exercises but will also complete daily symptom diaries during the same period. During the study, all participants will record their nausea and vomiting symptoms daily using a symptom diary. Researchers will assess the primary outcome by measuring the severity of nausea and vomiting on day seven. The study will monitor participants over the 7-day intervention period, with data collected to evaluate the breathing exercise's impact on symptoms.
CONDITIONS
Brief Title
Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant individuals aged 18 years or older
- Viable pregnancy with gestational age between 6 0/7 and 12 6/7 weeks confirmed by last menstrual period or ultrasound
- Diagnosed with mild to moderate nausea and vomiting of pregnancy (PUQE-24 score between 4 and 12)
- Ability to understand and read English
You will not qualify if you...
- Severe nausea and vomiting (PUQE score greater than 12) or hyperemesis gravidarum requiring hospitalization or intravenous fluids
- Pre-existing, active or acute respiratory conditions such as asthma or COPD
- History of severe anxiety disorders affecting breathing patterns
- Known deviated nasal septum
- Nausea and vomiting that started before pregnancy or due to causes other than pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 7 days
Participants perform alternate nostril breathing 3 times per day for 5-10 minutes per session over a 7-day period or receive usual care while completing a daily symptom diary.
1 orientation visit and daily symptom diary entries for 7 days
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
E
Erin Wesley
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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