Actively Recruiting
Alternation in the Human Microbiome With Commonly Used Topical Medications
Led by University of California, Davis · Updated on 2026-02-20
24
Participants Needed
1
Research Sites
713 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.
CONDITIONS
Official Title
Alternation in the Human Microbiome With Commonly Used Topical Medications
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults at least 18 years of age
You will not qualify if you...
- Individuals with known chronically active skin diseases, including atopic dermatitis, psoriasis, seborrheic dermatitis, and other autoimmune or inflammatory skin conditions
- Individuals who have used topical, intravenous, intramuscular, or oral antibiotics within the last 6 months
- Individuals with known allergies to any of the study medications
- Individuals younger than 18 years of age
- Adults unable to consent
- Non-English speaking individuals
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, Davis, Department of Dermatology
Sacramento, California, United States, 95816
Actively Recruiting
Research Team
E
Emanual Maverakis, MD
CONTACT
L
Lauren Downing
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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