Actively Recruiting
Altitude and Outcomes in Pediatric ARDS: A Multicenter Study
Led by Latin American Pediatric Collaborative Network · Updated on 2026-02-27
1600
Participants Needed
11
Research Sites
121 weeks
Total Duration
On this page
Sponsors
L
Latin American Pediatric Collaborative Network
Lead Sponsor
U
Universidad Nacional de Colombia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This multicenter observational study will evaluate the association between geographic altitude, availability of critical care resources, and clinical outcomes in children with pediatric acute respiratory distress syndrome (PARDS). Data on demographics, physiology, and hospital structure will be collected from PICUs located at different altitudes worldwide. The study aims to identify gaps in PARDS management and provide recommendations adapted to diverse resource settings.
CONDITIONS
Official Title
Altitude and Outcomes in Pediatric ARDS: A Multicenter Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 1 month (corrected gestational age) and 18 years
- Admission to a pediatric intensive care unit or facility caring for mechanically ventilated children
- Requirement of invasive mechanical ventilation
- Diagnosis of pediatric acute respiratory distress syndrome (PARDS) according to PALICC criteria, confirmed within 24 hours before or after endotracheal intubation
You will not qualify if you...
- Active perinatal lung diseases such as neonatal respiratory distress syndrome, pulmonary hemorrhage, persistent pulmonary hypertension of the newborn, early bronchopulmonary dysplasia, or meconium aspiration
- Receipt of extracorporeal membrane oxygenation (ECMO) prior to or within 24 hours of PARDS diagnosis
- Pre-established limitation of therapeutic effort (LTE) orders or palliative care directives before invasive mechanical ventilation
- Readmission to the PICU during the study period (only the first episode per patient included)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
Hospital del Niño Sor Teresa Huarte Tama
Sucre, Chuquisaca Department, Bolivia
Actively Recruiting
2
Clinica Indisa
Santiago, Chile
Actively Recruiting
3
Hospital Universitario Clinica San Rafael
Bogotá, DC, Colombia, 110411
Actively Recruiting
4
Sociedad de Cirugia de Bogota Hospital de San Jose
Bogotá, DC, Colombia, 110421
Actively Recruiting
5
Fundación HOMI
Bogotá, DC, Colombia, 111411
Actively Recruiting
6
Fundacion Hospital Infantil Los Angeles
Pasto, Departamento de Nariño, Colombia, 520002
Actively Recruiting
7
Clínica UROS S.A
Neiva, Huila Department, Colombia, 410010
Actively Recruiting
8
LaCardio
Bogotá, Colombia, 110131
Not Yet Recruiting
9
Hospital Nacional Adolfo Guevara Velasco
Cusco, Peru
Actively Recruiting
10
Centro Hospitalario Pereira Rossell
Montevideo, Montevideo Department, Uruguay, 11600
Actively Recruiting
11
Círculo Católico
Montevideo, Uruguay
Actively Recruiting
Research Team
P
PABLO VASQUEZ-HOYOS, MD, MSc
CONTACT
S
SEBASTIAN GONZALEZ-DAMBRAUSKAS, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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