Actively Recruiting

Age: 18Years +
All Genders
ID04295252

Cardiogenic Shock: a Prospective National Registry to Get Insights in Patients' Profile, Management and Outcome

Led by Niguarda Hospital · Updated on 2026-05-14

3000

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are collecting detailed information on patients experiencing cardiogenic shock (CS), a severe type of acute heart failure, who are admitted to Intensive Coronary Care Units. The study aims to better understand the profile, management, outcomes, and progression of these patients over time. It addresses the need for improved clinical classification and research on the varied causes and presentations of CS, especially given its high short-term mortality and the importance of specialized care centers. This observational registry includes all patients with cardiogenic shock admitted to Intensive Coronary Care Units from January 2020 through December 2030. The study tracks multiple clinical factors including the cause of shock, clinical presentation, current treatments, use of mechanical support devices, and patient outcomes. There are no interventions or treatments assigned by the study as it is focused on data collection and analysis. Participants will be followed for up to 10 years to monitor their clinical course, re-hospitalizations, and other outcomes. Researchers will collect information on clinical characteristics, management approaches, and patient evolution during their stay and long-term follow-up. The study involves reviewing medical data over this period to provide insights into how cardiogenic shock patients are treated and how they fare over time.

CONDITIONS

Brief Title

Altshock-2 REGISTRY

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Diagnosed with cardiogenic shock as defined by low blood pressure or need for support
  • Signs of poor tissue blood flow such as low venous oxygen saturation, elevated arterial lactates, or low urine output
  • Admitted to Intensive Coronary Care Units between January 2020 and December 2030
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 10 years

Participants who are admitted to Intensive Coronary Care Units with cardiogenic shock are observed to collect data on their clinical characteristics, management, and outcomes.

Follow-up visits as per routine clinical care over 10 years

Trial Site Locations

Total: 1 location

1

ASST GOM Niguarda

Milan, Italy, 20125

Actively Recruiting

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Research Team

A

Alice Sacco, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

SCAI stage reclassification at 24 h predicts outcome of cardiogenic shock: Insights from the Altshock-2 registry.

Nuccia Morici, Simone Frea, Maurizio Bertaina...

https://pubmed.ncbi.nlm.nih.gov/36378673