Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT07332260

Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study

Led by University Hospital of North Norway · Updated on 2026-04-22

10

Participants Needed

1

Research Sites

35 weeks

Total Duration

On this page

Sponsors

U

University Hospital of North Norway

Lead Sponsor

U

UiT The Arctic University of Norway

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to assess the feasibility and safety of faecal microbiota transplantation for Alzheimer's disease.

CONDITIONS

Official Title

Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Alzheimer's dementia mild to moderate stage
  • Presence of Alzheimer pathology core 1 biomarkers as defined by National Institute on Aging-Alzheimer's Association (NIA-AA) criteria (2024)
  • Capable of giving informed consent
Not Eligible

You will not qualify if you...

  • Contraindications for colonoscopy examination
  • Contraindications for Magnetic Resonance Imaging (MRI)
  • Life expectancy less than 1 year
  • Clinical frailty scale 7 or more
  • History of seizure disorder
  • History of brain tumour or intracranial bleed
  • Major psychiatric disorder such as schizophrenia, bipolar disorder, or major depressive disorder
  • Alcohol or substance abuse
  • Decompensated heart disease
  • Malignancy
  • Current use of anticoagulant treatment (dual acting oral anticoagulant or warfarin)
  • Pregnant or planning pregnancy
  • Colonic adenomas over 1 cm, tumours or signs of active colitis on colonoscopy
  • Status after colectomy or hemicolectomy
  • Inflammatory bowel disease
  • Immunocompromised individual
  • Receiving biological/antibody treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital of North Norway, Tromsø

Tromsø, Troms, Norway, 9016

Actively Recruiting

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Research Team

M

Mona Dixon Gundersen, MBChB, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Alzheimer's Disease and Faecal Microbiota Transplantation -a Pilot Study | DecenTrialz