Noise and Ultrafine Particulate Matter Induced Cardiovascular and Cerebral Damage and Lifestyle Intervention to Reduce Cardiovascular Health Risk

What this Trial Is About

Researchers are studying how exposure to ultrafine particulate matter PM0.1 and noise pollution affects the risk of cardiovascular diseases and metabolic disorders in adults aged 45 to 64 living in Kaunas City. The study combines an observational survey of about 1,000 residents with a clinical trial involving 180 participants who show early signs of metabolic syndrome. The goal is to see if these environmental factors increase health risks and whether lifestyle changes can help reduce them. In the clinical trial, participants are randomly assigned to one of three groups a control group maintaining their usual habits, a group encouraged to take daily 30-minute brisk walks in green spaces, and a group following a Mediterranean diet with dietary counseling. The interventions last for 7 days, during which physical activity is tracked with wristband sensors, and dietary intake is supervised. Participants visit the clinic twice, on Day 1 and Day 8, for health measurements and blood sample collection. Participants complete health and lifestyle questionnaires, wear wristband sensors to monitor activity, heart rate, and sleep, and undergo clinical assessments including blood pressure, waist circumference, body composition, and blood tests for metabolic and inflammatory markers. Researchers analyze these data to understand the impact of environmental exposure and lifestyle changes on cardiovascular and metabolic health. The studys findings aim to guide public health strategies to reduce disease risks related to pollution and lifestyle.

Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)