Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
NCT05737732

The Ambient Light Multiple Myeloma Study

Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-06-03

200

Participants Needed

2

Research Sites

228 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.

CONDITIONS

Official Title

The Ambient Light Multiple Myeloma Study

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Multiple Myeloma
  • Scheduled for their first Autologous Stem Cell Transplant procedure
  • 21 years of age or older
  • Able to provide informed consent
  • Proficient in English
Not Eligible

You will not qualify if you...

  • Prior Autologous Stem Cell Transplant procedure
  • Pregnancy
  • Eye diseases limiting light processing
  • Secondary cancer diagnosis within the last 5 years
  • Severe sleep disorders
  • History of bipolar disorder or manic episodes
  • Severe psychological impairment
  • Previous use of light therapy
  • Active infection including COVID-19

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Icahn Schoool of Medicine at Mount Sinai

New York, New York, United States, 10029

Actively Recruiting

2

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

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Research Team

B

Barbara Plitnick, BSN

CONTACT

M

Mariana Figueiro, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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