Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT06848868

Ambulatory Flexible URS for UTUC Surveillance

Led by Chinese University of Hong Kong · Updated on 2025-09-15

10

Participants Needed

2

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a a prospective single-arm pilot study to investigate the safety and feasibility of flexible ureteroscopy under local anaesthesia. All consecutive patients who have undergone kidney-sparing surgery for managing upper tract urothelial carcinoma will be screened for study eligibility. The primary outcome is the procedural technical success rate. Secondary outcomes include the 30-day complication rate following flexible ureteroscopy, readmission rates, cost analysis, and patient-reported outcomes. Ureterorenoscopy will be conducted in the recruited patients under local anaesthesia in the ambulatory urology centre. Procedural details, technical success rates, adverse events and patient reported outcomes will be documented. The anticipated risks of this intervention are not expected to exceed those associated with the standard of care, that is ureterorenoscopy under anaesthesia. This pilot study aims to recruit a total of 10 subjects to assess the safety and feasibility of flexible ureterorenoscopy in an ambulatory care setting.

CONDITIONS

Official Title

Ambulatory Flexible URS for UTUC Surveillance

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 years or older
  • Capable of giving informed consent
  • Having undergone kidney-sparing surgery (endoscopic operation or segmental ureterectomy)
Not Eligible

You will not qualify if you...

  • Allergy to transurethral lidocaine jelly
  • On anticoagulation or anti-platelet medication with contraindications for cessation prior to the procedure
  • Structural abnormalities in the upper urinary tract on the intended side of examination

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Prince of Wales Hospital

Hong Kong, Hong Kong

Actively Recruiting

2

The Chinese University of Hong Kong

Hong Kong, Hong Kong

Not Yet Recruiting

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Research Team

J

Jeremy Teoh Teoh, FHKAM, FRCS, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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