Actively Recruiting
Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung Disease
Led by University of Alberta · Updated on 2026-05-06
60
Participants Needed
1
Research Sites
61 weeks
Total Duration
On this page
Sponsors
U
University of Alberta
Lead Sponsor
A
Alberta Boehringer Ingelheim Collaboration
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators plan to conduct a study to find out if giving portable oxygen therapy (during physical activity) to patients with interstitial lung disease will improve quality of life, exercise tolerance, shortness of breath, and blood vessel function. Oxygen will be provided for a period of 8 weeks. Additionally, the investigators plan to investigate if it is helpful to deliver individualized support when providing oxygen therapy, through check-in phone calls with a respiratory therapist and by providing additional educational material.
CONDITIONS
Official Title
Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 85 years
- Diagnosis of fibrotic interstitial lung disease (all ILD sub-groups)
- Normal oxygen saturation at rest (SpO2 > 90%) but develop exertional hypoxemia (SpO2 80-89%) during activity measured by 6-minute walk test
You will not qualify if you...
- Use of home oxygen therapy within the past year for ILD or related conditions
- Need for non-invasive ventilation
- Significant cardiovascular, metabolic, neuromuscular, or other diseases causing breathlessness or abnormal exercise responses
- Musculoskeletal injuries preventing cycle ergometry or walking
- Peripheral vascular disease (excluded from vascular function testing)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Physiology Laboratory
Edmonton, Alberta, Canada, T6G2R3
Actively Recruiting
Research Team
M
Matt Rieger, PhD
CONTACT
D
Desi Fuhr, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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