Actively Recruiting
AMI Construction in Lower Extremity Residual Limbs
Led by Brigham and Women's Hospital · Updated on 2025-10-20
26
Participants Needed
3
Research Sites
344 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
M
Massachusetts Institute of Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will involve the development of a novel approach to lower extremity residual limb surgical revision that offers the promise of augmenting volitional motor control, restore proprioception and reverse atrophy
CONDITIONS
Official Title
AMI Construction in Lower Extremity Residual Limbs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages of 18-65
- Has already undergone a standard above knee (AKA) or below knee (BKA) amputation
- Experiences symptoms such as intractable pain, skin deterioration on or around the stump, or other discomfort from the stump
- Has intact wound healing ability
- Has adequate communication skills
- Is highly motivated
You will not qualify if you...
- Inadequate health to undergo surgery with standard anesthesia (e.g., heart or lung problems)
- Impaired wound healing
- Extensive peripheral neuropathies
- Active smoker
- History of poor compliance
- Women who are pregnant or planning pregnancy before surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Walter Reed National Military Medical Center
Bethesda, Maryland, United States, 20889
Not Yet Recruiting
2
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
3
Massachusetts Institute of Technology
Cambridge, Massachusetts, United States, 02139
Actively Recruiting
Research Team
M
Matthew J Carty, MD
CONTACT
R
Research Coordinators
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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