Actively Recruiting

Age: 18Years +
All Genders
NCT06659835

Amino Acid Loss During Continuous Renal Replacement Therapy

Led by Medical University of Vienna · Updated on 2025-05-25

30

Participants Needed

1

Research Sites

94 weeks

Total Duration

On this page

Sponsors

M

Medical University of Vienna

Lead Sponsor

K

Karolinska Institutet

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are: What amount of amino acids is lost over the duration of continuous renal replacement therapy? How do amino acid plasma concentrations change over time in patients with and without continuous renal replacement therapy? Amino acid concentrations will be measured in the effluent and in the plasma of patients receiving continuous renal replacement therapy as part of their regular medical care. In addition, plasma concentrations of amino acids will be studied in patients without renal replacement therapy.

CONDITIONS

Official Title

Amino Acid Loss During Continuous Renal Replacement Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Postoperative ICU patients
  • Age 218 years or older
  • Patients receiving enteral or parenteral nutrition as per internal standard procedures
  • CRRT treatment planned for CRRT group (including CVVHD, CVVHDF, CVVH types)
  • No current or previous (within 30 days) continuous or intermittent renal replacement therapy for non-CRRT group
  • No chronic kidney disease stage G3-G5 for non-CRRT group
Not Eligible

You will not qualify if you...

  • Preoperative intensive care patients
  • Patients with liver cirrhosis stage 1-3 according to Child-Pugh classification
  • Patients with acute liver failure

AI-Screening

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Trial Site Locations

Total: 1 location

1

Medical University of Vienna

Vienna, State of Vienna, Austria, 1090

Actively Recruiting

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Research Team

S

Sarah Yadavalli, Dr.

CONTACT

A

Arabella Fischer, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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