Actively Recruiting
AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses
Led by Houssam Farres, M.D. · Updated on 2025-08-12
15
Participants Needed
1
Research Sites
367 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the safety of allogeneic Adipose Derived Mesenchymal Stem Cells (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its efficacy on improving access maturation and primary anastomotic patency.
CONDITIONS
Official Title
AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient between 18 and 85 years old
- Patient currently planned for creation of an upper extremity AV fistula with suitable anatomy
- Ability to communicate meaningfully with investigative staff, competence to give written informed consent, and ability to comply with entire study procedures
- Life expectancy of at least 24 months
- If female, must be post-menopausal or not able to have children with documentation or pregnancy testing
You will not qualify if you...
- Malignancy or treatment for malignancy within the previous 6 months
- Immunodeficiency including AIDS / HIV or active autoimmune disease
- Documented hypercoagulable state or history of 2 or more deep vein thromboses or other spontaneous intravascular thrombotic events
- Treatment with any investigational drug or device within 60 days prior to study entry
- Any condition that would prevent adequate evaluation of AMSCs and AVF safety and efficacy
- History of failed organ transplant on immunosuppression
- Known active infection being treated
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224
Actively Recruiting
Research Team
R
Reagan Dukes
CONTACT
M
Mauricia Buchanan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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