Actively Recruiting
Amygdala and dLPFC MRI-TIS for Depression in Adolescents
Led by Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University · Updated on 2024-06-11
60
Participants Needed
1
Research Sites
48 weeks
Total Duration
On this page
Sponsors
S
Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University
Lead Sponsor
R
Ruijin Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study utilizes a non-invasive deep brain stimulation (temporal interference, TI) technique primarily targeting the amygdala to preliminarily explore the clinical efficacy and potential mechanisms of MRI-compatible TI technology in regulating the amygdala in adolescent depressive disorders.
CONDITIONS
Official Title
Amygdala and dLPFC MRI-TIS for Depression in Adolescents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged between 14 and 18 years, any gender
- Diagnosed with depression according to DSM-5 by the study physician
- HAMD-17 score of 17 or higher
- No changes in antidepressant medication from 30 days before consent through the study
- Ability to understand the study and follow protocol, with informed consent provided
You will not qualify if you...
- History of psychiatric or neurological disorders affecting study evaluation
- History of seizures or epilepsy
- Presence of metallic objects in the skull or metallic cardiac implants
- Diagnosis of organic brain disease, significant head trauma, or neurosurgery
- Prior electroconvulsive therapy or other physical therapies like transcranial magnetic stimulation
- Significant risk of suicidal thoughts or behavior as assessed by the researcher
- Pregnant or breastfeeding
- Participation in other clinical interventional trials
- Any other condition deemed unsuitable by the investigator for the intervention
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Pudong New Area Mental Health Center
Shanghai, Shanghai Municipality, China
Actively Recruiting
Research Team
J
JINGJING HUANG, MD PhD
CONTACT
C
Chencheng Zhang, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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