A National Study to Collect Clinical and Genetic Data on Amyotrophic Lateral Sclerosis ALS Patients in Thailand

What this Trial Is About

Researchers are conducting a prospective, observational registry study to collect detailed clinical, genetic, and outcome data from patients diagnosed with amyotrophic lateral sclerosis ALS across Thailand. The study aims to build a national database to better understand ALS epidemiology, clinical features, disease progression, and treatment outcomes. This registry will also provide a foundation for future clinical and translational research in ALS. Patients diagnosed with ALS will be enrolled from major academic hospitals and specialized neuromuscular centers across Thailand. No experimental treatments are involved patients will continue receiving standard care as determined by their doctors. Data will be gathered through standardized assessments such as the ALS Functional Rating Scale-Revised ALSFRS-R, clinical staging systems, motor and respiratory function tests, quality-of-life questionnaires, and cognitive and behavioral evaluations. Participants will be followed over time with data securely stored in an electronic database that meets privacy standards. Researchers will track survival over 10 years along with functional decline, disease progression, respiratory health, quality of life changes, cognitive status, genetic and environmental risk factors, and healthcare usage. The study will last for a long-term period, aiming to provide comprehensive insights into ALS in Thailand.

Amyotrophic Lateral Sclerosis Registry in Thailand