Actively Recruiting
Efficacy of Combined US-Guided Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA With Fentanyl on Preventing Tourniquet Pain in Forearm Surgery: A Randomized Clinical Trial
Led by Al-Azhar University · Updated on 2026-01-06
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing different nerve block techniques and patient-controlled analgesia to reduce tourniquet pain during forearm surgery. The trial focuses on the effectiveness of interscalene brachial plexus block (ISBPB), intercostobrachial nerve (ICBN) block, and supraclavicular brachial plexus block (SCBPB) combined with fentanyl for pain control. This randomized study aims to better understand which method lowers the incidence and severity of pain caused by a tourniquet used during surgery. All participants will receive a supraclavicular block as their primary anesthetic using 20 to 30 mL of 0.5% bupivacaine under ultrasound guidance. The study groups differ by additional treatments: one group receives an interscalene brachial plexus block with 10 mL of 0.125% bupivacaine around the nerve roots; another group receives an intercostobrachial nerve block with 10 mL of 0.5% bupivacaine near the second and third intercostal space; the third group uses patient-controlled analgesia with fentanyl. Midazolam may be given on request, and fentanyl is administered if pain occurs during surgery. Participants will be monitored for tourniquet pain incidence within two hours after surgery, along with hemodynamic changes, adverse reactions, and patient satisfaction up to 24 hours. Pain quality and location will be documented if pain arises during surgery. The study involves patients aged 18 to 70 undergoing forearm orthopedic or plastic surgery with specific anesthesia eligibility. Safety and effectiveness data collected during and after surgery will help determine the best pain management technique for this setting.
CONDITIONS
Brief Title
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged more than 18 years
- ASAI-III patients
- Scheduled for orthopedic or plastic surgery distal to the elbow
- Anticipated tourniquet duration greater than 45 minutes
- Desire regional anesthesia as the primary anesthetic
You will not qualify if you...
- Contraindication to regional anesthesia
- Allergy to local anesthetics
- Primary block failure
- Desire for deep intraoperative sedation
- Clinically significant cognitive impairment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 hours during surgery and immediate postoperative period
Participants receive a supraclavicular block as the primary anesthetic, combined with either an interscalene analgesia, intercostobrachial nerve block, or patient-controlled analgesia with fentanyl during forearm surgery.
1 surgical procedure visit
Duration - 24 hours post-surgery
Participants are monitored for pain incidence, hemodynamics, adverse reactions within 2 hours after surgery, and their satisfaction is assessed at 24 hours.
1 follow-up visit within 24 hours
Trial Site Locations
Total: 1 location
1
Facualty of Medicine(Damietta), Al Azhar University
Damietta, Egypt, 34711
Actively Recruiting
Research Team
N
Neveen A. Kohaf, Ph.D
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here