Actively Recruiting

Phase 4
Age: 18Years - 70Years
All Genders
ID05602636

Efficacy of Combined US-Guided Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA With Fentanyl on Preventing Tourniquet Pain in Forearm Surgery: A Randomized Clinical Trial

Led by Al-Azhar University · Updated on 2026-01-06

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing different nerve block techniques and patient-controlled analgesia to reduce tourniquet pain during forearm surgery. The trial focuses on the effectiveness of interscalene brachial plexus block (ISBPB), intercostobrachial nerve (ICBN) block, and supraclavicular brachial plexus block (SCBPB) combined with fentanyl for pain control. This randomized study aims to better understand which method lowers the incidence and severity of pain caused by a tourniquet used during surgery. All participants will receive a supraclavicular block as their primary anesthetic using 20 to 30 mL of 0.5% bupivacaine under ultrasound guidance. The study groups differ by additional treatments: one group receives an interscalene brachial plexus block with 10 mL of 0.125% bupivacaine around the nerve roots; another group receives an intercostobrachial nerve block with 10 mL of 0.5% bupivacaine near the second and third intercostal space; the third group uses patient-controlled analgesia with fentanyl. Midazolam may be given on request, and fentanyl is administered if pain occurs during surgery. Participants will be monitored for tourniquet pain incidence within two hours after surgery, along with hemodynamic changes, adverse reactions, and patient satisfaction up to 24 hours. Pain quality and location will be documented if pain arises during surgery. The study involves patients aged 18 to 70 undergoing forearm orthopedic or plastic surgery with specific anesthesia eligibility. Safety and effectiveness data collected during and after surgery will help determine the best pain management technique for this setting.

CONDITIONS

Brief Title

Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged more than 18 years
  • ASAI-III patients
  • Scheduled for orthopedic or plastic surgery distal to the elbow
  • Anticipated tourniquet duration greater than 45 minutes
  • Desire regional anesthesia as the primary anesthetic
Not Eligible

You will not qualify if you...

  • Contraindication to regional anesthesia
  • Allergy to local anesthetics
  • Primary block failure
  • Desire for deep intraoperative sedation
  • Clinically significant cognitive impairment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 2 hours during surgery and immediate postoperative period

Participants receive a supraclavicular block as the primary anesthetic, combined with either an interscalene analgesia, intercostobrachial nerve block, or patient-controlled analgesia with fentanyl during forearm surgery.

1 surgical procedure visit

Follow-up

Duration - 24 hours post-surgery

Participants are monitored for pain incidence, hemodynamics, adverse reactions within 2 hours after surgery, and their satisfaction is assessed at 24 hours.

1 follow-up visit within 24 hours

Trial Site Locations

Total: 1 location

1

Facualty of Medicine(Damietta), Al Azhar University

Damietta, Egypt, 34711

Actively Recruiting

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Research Team

N

Neveen A. Kohaf, Ph.D

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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