Actively Recruiting
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries: A Randomized Trial
Led by Kafrelsheikh University · Updated on 2025-02-06
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Knee surgeries often cause significant pain after the operation, which can delay movement and recovery. This trial aims to compare how well blocking the nerve to the vastus lateralis muscle works against blocking the lateral femoral cutaneous nerve to manage pain and improve function after knee surgery. The study uses recent ultrasound-guided techniques to target these specific nerves for pain relief. Participants will be randomly assigned to receive either the vastus lateralis nerve block or the lateral femoral cutaneous nerve block. Both groups will receive an injection of 5 ml of bupivacaine 0.5% to block the respective nerves. These procedures are performed during the surgery under spinal anesthesia. The trial is double-blinded, meaning neither the patients nor the researchers know which nerve block is given to ensure unbiased results. During the study, researchers will monitor pain levels 24 hours after surgery, time until the first request for additional pain relief, total morphine use, block procedure time, patient satisfaction, hospital stay length, and any side effects during the first 24 hours. The hospital stay may last up to one week. Participants will undergo assessments related to pain and recovery, with close monitoring to evaluate the effectiveness and safety of each nerve block over this period.
CONDITIONS
Brief Title
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 218 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status from I to III.
- Underwent knee surgeries under spinal anesthesia.
You will not qualify if you...
- Pregnancy.
- Coagulopathy.
- Neuromuscular disorders.
- Hematological disorders.
- Mental disorders.
- History of multiple traumas or anesthesia drug allergies.
- Local skin infection at the block site.
- Body mass index (BMI) greater than 40.
- Opioid analgesics or abusing opioids.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Intraoperative period
Participants receive either a vastus lateralis nerve block or a lateral femoral cutaneous nerve block with bupivacaine during knee surgery under spinal anesthesia.
1 visit during surgery
Duration - Up to 1 week postoperatively
Participants are observed for pain levels, analgesia needs, morphine consumption, patient satisfaction, adverse events, and length of hospital stay after surgery.
Daily assessments during hospital stay (up to one week)
Trial Site Locations
Total: 1 location
1
Kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, Egypt, 33516
Actively Recruiting
Research Team
S
Sherif K Arafa, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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