Actively Recruiting
Analgesic Efficacy of External Oblique Intercostal Block Versus Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy
Led by Cairo University · Updated on 2024-09-19
63
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two types of ultrasound-guided nerve blocks to manage pain during and after open nephrectomy surgery in cancer patients. The study aims to evaluate the effectiveness of the external oblique intercostal block versus the subcostal transversus abdominis plane block in providing pain relief. Open nephrectomy can cause severe immediate and chronic pain, and regional anesthesia techniques are used to reduce opioid use and improve patient comfort. Participants are divided into three groups: one receives the oblique subcostal transversus abdominis plane block, another receives the external oblique intercostal block, and the control group receives intravenous morphine after general anesthesia induction. Both nerve blocks involve injecting bupivacaine guided by ultrasound, aiming to cover the nerves supplying the surgical area. General anesthesia is maintained with standard medications during surgery. During the study, pain levels will be assessed 24 hours post-surgery alongside opioid and morphine consumption, heart rate, arterial pressure, time until additional pain relief is needed, and any complications. Monitoring lasts through surgery and up to 24 hours after. Participants will be closely evaluated for pain management effectiveness and safety throughout the study period.
CONDITIONS
Brief Title
Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Both male and female participants
- Classified as American Society of Anesthesiologists (ASA) class II or III
- Cancer patients scheduled for open nephrectomy surgery
You will not qualify if you...
- Patient refusal to participate
- Skin lesions or infections at the needle insertion site
- Cognitive disorders
- History of psychiatric disorders or drug abuse
- Allergy to medications used in the study
- Classified as ASA class IV
- Coagulopathy (bleeding disorders)
- Body mass index (BMI) over 35
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 hours during surgery
Participants receive either an external oblique intercostal block, a subcostal transversus abdominis plane block, or IV morphine as part of their surgical pain management during open nephrectomy.
1 surgical visit (in-person)
Duration - 24 hours after surgery
Participants are monitored for pain levels, opioid consumption, and any complications for 24 hours after surgery.
1 follow-up visit (in-person)
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 11796
Actively Recruiting
Research Team
A
Ahmed A Abdelbaset, Master
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here