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Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06820190

Comparing Pain Relief of Mid-Transverse Process to Pleura Block and Morphine PCA in Adults with Idiopathic Scoliosis Undergoing Spinal Fusion Surgery

Led by Tanta University · Updated on 2026-01-07

40

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing the pain relief effects of a multiple mid-transverse process to pleura MTP block with patient-controlled analgesia PCA using morphine in adults with idiopathic scoliosis undergoing posterior spinal fusion surgery. The study addresses the challenges of managing postoperative pain and hospitalization length in this group. Regional anesthesia techniques like epidural analgesia and paravertebral blocks, enhanced by ultrasound guidance, have become important in multimodal pain management. The MTP block and erector spinae plane ESP block are newer methods being evaluated for postoperative pain control. Participants are randomly assigned to one of two groups. One group receives multiple MTP blocks after anesthesia induction. The other group uses intravenous PCA with morphine, starting with a loading dose before surgery ends, followed by patient-controlled doses with specified lockout intervals and background infusion rates. This randomized, double-blind trial compares these two pain management approaches during and after surgery. Throughout the study, researchers monitor pain levels 24 hours after surgery as the primary outcome. They also track intraoperative fentanyl use, timing of first rescue analgesia, total morphine use, blood pressure and heart rate every 15 minutes during surgery, patient satisfaction, and any complications within 24 hours postoperatively. The overall goal is to better understand and improve pain control strategies in scoliosis surgery patients.

CONDITIONS

Brief Title

Analgesic Efficacy of Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 18 years
  • Both sexes
  • American Society of Anesthesiology (ASA) physical status I-II
  • Idiopathic scoliosis patients undergoing posterior spinal fusion surgery
Not Eligible

You will not qualify if you...

  • Patients with pre-existing infection at block site
  • Known allergy to study drugs
  • Coagulation disorder
  • History of psychiatric illness
  • Pre-existing neurological deficits
  • Patient with morbid obesity (body mass index >40 kg/m2)
  • Presence of any pre-operative pain or history of chronic pain
  • History of regular analgesic use

Research Team

M

Mohammed S Elsharkawy, MD

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