Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID06664177

Comparison of the Postoperative Analgesic Efficacy of Quadratus Lumborum Block and Transversalis Fascia Block in Inguinal Hernia Surgery

Led by Gaziosmanpasa Research and Education Hospital · Updated on 2025-12-01

60

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the postoperative pain relief effectiveness of two types of nerve blocks, the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block, in adults undergoing elective open inguinal hernia surgery. The study aims to compare how long it takes before patients need their first additional pain medication after surgery, as well as total pain relief medication use and pain scores over 24 hours. The goal is to improve pain management while reducing opioid-related side effects and supporting faster recovery. Participants will be randomly assigned to receive either the anterior Quadratus Lumborum Block or the Transversalis Fascia Plane Block after surgery. Both procedures involve injecting 20 mL of 0.25% bupivacaine guided by ultrasound while the patient is positioned on their side. All patients receive spinal anesthesia before surgery and a dose of intravenous paracetamol afterward. The nerve blocks are applied in a block room immediately post-surgery, with monitoring for 30 minutes following the procedure. Throughout the 24-hour period after surgery, patients will be assessed at 2, 4, 8, 12, and 24 hours to record pain levels using a Numeric Rating Scale, time to first use of additional pain medication, and total analgesic consumption. Side effects like nausea and vomiting will also be monitored. If pain scores exceed 3, rescue analgesics such as intravenous ibuprofen or dexketoprofen may be administered. This detailed follow-up helps determine which nerve block provides better pain control and fewer side effects to improve patient comfort and recovery.

CONDITIONS

Brief Title

Analgesic Efficacy of Quadratus Lumborum vs. Transversalis Fascia Block in Inguinal Hernia Surgery

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18 to 65
  • ASA physical status classification 1 or 2
Not Eligible

You will not qualify if you...

  • Allergy to local anesthetics
  • Infection at the procedure site
  • Body mass index over 35 kg/m8
  • Bleeding disorders or use of anticoagulant medications
  • Chronic use of analgesics or opioids
  • Mental or psychiatric disorders
  • ASA classification 3 or 4 (including severe COPD, history of cerebrovascular events, liver or kidney disease)

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surgery and Immediate Post-operative Care

Duration - Day of surgery

Participants undergo elective open inguinal hernia surgery under spinal anesthesia and receive either the anterior Quadratus Lumborum Block or the Transversalis Fascia Plane Block immediately after surgery.

1 visit (in-person)

Post-operative Follow-up

Duration - 24 hours

Participants are monitored and assessed for pain, analgesic use, and side effects at several time points after surgery.

Visits at 2, 4, 8, 12, and 24 hours post-surgery

Trial Site Locations

Total: 1 location

1

Gaziosmanpasa Research and Training Hospital

Istanbul, Turkey (Türkiye), 34255

Actively Recruiting

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Research Team

S

serpil Sehirlioglu, MD

D

DÖNDÜ GENÇ MORALAR, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Published Research Related To This Trial

Preemptive analgesic efficacy of ultrasound-guided transversalis fascia plane block in children undergoing inguinal herniorrhaphy: a randomized, double-blind, controlled study.

Ibrahim Abdelbaser, Nabil A Mageed, El-Sayed M El-Emam...

https://pubmed.ncbi.nlm.nih.gov/33307633

A Prospective, randomized comparative study between ultrasound-guided posterior quadratus lumborum block and ultrasound-guided ilioinguinal/iliohypogastric nerve block for pediatric inguinal herniotomy.

Artid Samerchua, Prangmalee Leurcharusmee, Kachain Panichpichate...

https://pubmed.ncbi.nlm.nih.gov/32030845

Ultrasound-guided quadratus lumborum block for postoperative pain control in patients undergoing unilateral inguinal hernia repair, a comparative study between two approaches.

Abeer Ahmed, Maher Fawzy, Mohamed A R Nasr...

https://pubmed.ncbi.nlm.nih.gov/31623572