Actively Recruiting

Age: 10Years - 15Years
All Genders
NCT07254351

Analysis of the Biomechanical Impact of Lower Limb Length Inequality in PEDiatrics

Led by Hospices Civils de Lyon · Updated on 2026-04-17

100

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Lower limb length discrepancy (LLD) is a frequent condition in pediatric orthopedics. Even moderate discrepancies can induce pelvic obliquity and compensatory scoliosis, modifying the distribution of joint loads at the hips and lumbar spine. These biomechanical imbalances are suspected to contribute to early degenerative conditions such as osteoarthritis or chronic low back pain. The aim of this study is to quantify the biomechanical impact of LLD in children aged 10 to 15 years, using a combination of low dose biplanar EOS imaging (EOS Imaging System) and synchronized ground reaction force (GRF) measurements from integrated force platforms. These data will be used in musculoskeletal models developed in collaboration with the Biomechanics and Impact Mechanics Laboratory (LBMC, Laboratoire de Biomécanique et Mécanique des Chocs), enabling the estimation of hip joint and lumbar intervertebral disc loads. This is the first pediatric study integrating EOS imaging, force platforms, and personalized musculoskeletal modeling to explore the mechanical consequences of LLD. The findings are expected to improve clinical reasoning and guide early therapeutic strategies.

CONDITIONS

Official Title

Analysis of the Biomechanical Impact of Lower Limb Length Inequality in PEDiatrics

Who Can Participate

Age: 10Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 10 to 15 years
  • Anatomical lower limb length discrepancy greater than 5 mm, clinically measured
  • EOS imaging recommended by pediatric orthopedic surgeon in routine care
  • Ability to stand still for 30 seconds without assistance
  • Covered by social security
  • Parental consent and non-opposition obtained
Not Eligible

You will not qualify if you...

  • Functional or postural lower limb length discrepancy without true anatomical difference
  • History of major pelvic or spinal surgery
  • Severe neurological or orthopedic condition preventing standing (e.g., cerebral palsy, progressive myopathy)
  • Fixed equinus deformity preventing foot support
  • Major lower limb deformity such as severe genu varum or valgum
  • Contraindication or inability to undergo EOS imaging

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospices Civils de Lyon Service d'Orthopédie et de Traumatologie

Bron, France, 69500

Actively Recruiting

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Research Team

T

Thierry HAUMONT, MD, PhD

CONTACT

D

Dimitri HERRERA-NATIVI

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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