Actively Recruiting
Cerebrospinal Fluid Leak Incidence, Management and Risk Factor After Supratentorial Craniotomy for Intracranial Tumors: a Prospective Observational Study
Led by Medical University of Warsaw · Updated on 2026-05-22
200
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying cerebrospinal fluid leakage after supratentorial craniotomy, a surgery performed on the upper part of the brain to remove intracranial tumors. This leakage can occur when the protective covering of the brain, called the dura, does not close properly after surgery. Leakage can lead to wound healing problems, infections, longer hospital stays, and delays in additional treatments like radiotherapy or chemotherapy. Although less common in supratentorial surgeries than others, cerebrospinal fluid leakage remains a challenging complication that has not been well studied in this patient group. This observational study will follow patients undergoing supratentorial craniotomy to remove brain tumors. The study will track how often cerebrospinal fluid leaks occur, identify patient and surgical factors that increase risk, and observe how these leaks are treated. Data collection will include tumor characteristics, types of dural closure, materials used, and treatment approaches. The study will observe patients for six weeks after surgery, which aligns with the usual start of additional cancer treatments. Participants will be monitored for fluid leakage signs, infections at the surgical site, and any need for extra medical visits or hospital stays related to leakage. Researchers will evaluate the timing of leaks and details of surgical techniques used. The goal is to better understand leakage incidence, risk factors, and management to improve recovery after brain tumor surgery.
CONDITIONS
Brief Title
Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female at least 18 years old
- Qualified for a craniotomy due to supratentorial intracranial tumor
You will not qualify if you...
- Revision surgery due to recurrent brain tumor
- Emergency neurosurgical procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Hospitalization period following surgery
Participants undergo supratentorial craniotomy for intracranial tumor removal followed by immediate post-operative care to monitor for cerebrospinal fluid leakage and related complications.
In-hospital monitoring visits during initial recovery
Duration - 6 weeks postoperatively
Participants are observed for 6 weeks after surgery to monitor the occurrence of cerebrospinal fluid leakage, surgical site infections, and other complications, as well as to assess treatments and recovery progress.
Follow-up visits over 6 weeks post-surgery
Trial Site Locations
Total: 1 location
1
Department of Neurosurgery of Medical Univeristy of Warsaw
Warsaw, Poland, 02-097
Actively Recruiting
Research Team
M
Michal Senger, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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