Actively Recruiting

Age: 18Years +
All Genders
ID07411690

Cerebrospinal Fluid Leak Incidence, Management and Risk Factor After Supratentorial Craniotomy for Intracranial Tumors: a Prospective Observational Study

Led by Medical University of Warsaw · Updated on 2026-05-22

200

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying cerebrospinal fluid leakage after supratentorial craniotomy, a surgery performed on the upper part of the brain to remove intracranial tumors. This leakage can occur when the protective covering of the brain, called the dura, does not close properly after surgery. Leakage can lead to wound healing problems, infections, longer hospital stays, and delays in additional treatments like radiotherapy or chemotherapy. Although less common in supratentorial surgeries than others, cerebrospinal fluid leakage remains a challenging complication that has not been well studied in this patient group. This observational study will follow patients undergoing supratentorial craniotomy to remove brain tumors. The study will track how often cerebrospinal fluid leaks occur, identify patient and surgical factors that increase risk, and observe how these leaks are treated. Data collection will include tumor characteristics, types of dural closure, materials used, and treatment approaches. The study will observe patients for six weeks after surgery, which aligns with the usual start of additional cancer treatments. Participants will be monitored for fluid leakage signs, infections at the surgical site, and any need for extra medical visits or hospital stays related to leakage. Researchers will evaluate the timing of leaks and details of surgical techniques used. The goal is to better understand leakage incidence, risk factors, and management to improve recovery after brain tumor surgery.

CONDITIONS

Brief Title

Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female at least 18 years old
  • Qualified for a craniotomy due to supratentorial intracranial tumor
Not Eligible

You will not qualify if you...

  • Revision surgery due to recurrent brain tumor
  • Emergency neurosurgical procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Hospitalization period following surgery

Participants undergo supratentorial craniotomy for intracranial tumor removal followed by immediate post-operative care to monitor for cerebrospinal fluid leakage and related complications.

In-hospital monitoring visits during initial recovery

Post-operative Follow-up

Duration - 6 weeks postoperatively

Participants are observed for 6 weeks after surgery to monitor the occurrence of cerebrospinal fluid leakage, surgical site infections, and other complications, as well as to assess treatments and recovery progress.

Follow-up visits over 6 weeks post-surgery

Trial Site Locations

Total: 1 location

1

Department of Neurosurgery of Medical Univeristy of Warsaw

Warsaw, Poland, 02-097

Actively Recruiting

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Research Team

M

Michal Senger, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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