Actively Recruiting

Age: 18Years +
FEMALE
NCT06706557

Analysis of Circulating Tumor DNA (ctDNA) in HER2-low Advanced/Metastatic Breast Cancer

Led by European Institute of Oncology · Updated on 2026-03-24

30

Participants Needed

1

Research Sites

363 weeks

Total Duration

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AI-Summary

What this Trial Is About

A Pilot study on circulating tumor DNA (ctDNA) in advanced/metastatic breast cancer with low levels of HER2 expression (HER2 low)

CONDITIONS

Official Title

Analysis of Circulating Tumor DNA (ctDNA) in HER2-low Advanced/Metastatic Breast Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with HER2-low breast cancer defined as IHC score 1+ or 2+ and not amplified by ISH test confirmed by local lab
  • Breast cancer in advanced or metastatic stage before treatment
  • Signed written informed consent before joining the study
  • Accessible for follow-up visits during the study
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

European Institute of Oncology

Milan, MI, Italy, 20141

Actively Recruiting

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Research Team

N

Nicola Fusco, MD

CONTACT

F

francesca lombardi, biologist

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Analysis of Circulating Tumor DNA (ctDNA) in HER2-low Advanced/Metastatic Breast Cancer | DecenTrialz