Actively Recruiting
Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing
Led by Baylor Research Institute · Updated on 2026-05-05
50
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants thereof (transit time, Pa, Pd) in patients before and after intracoronary nitroglycerine.
CONDITIONS
Official Title
Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 or older
- Being evaluated for angina with non-obstructive coronary arteries (ANOCA or INOCA)
- Clinical suspicion for angina
- Able to comply with the study protocol
- Provide written informed consent before participation
You will not qualify if you...
- Existing coronary artery disease
- Previous percutaneous coronary interventions
- Use of long-acting nitrate therapies within 48 hours
- Use of PDE-5 inhibitors (sildenafil, tadalafil) within 48 hours
- Any condition or co-morbidity posing significant hazard as judged by investigator
- Children under 18 years, prisoners, pregnant people, or those unable to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Baylor Scott & White The Heart Hospital - Plano
Plano, Texas, United States, 75093
Actively Recruiting
Research Team
B
Bonnie Ostergren
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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