Study of High-Intensity Exercise Effects in Adults With Chronic Kidney Disease on Dialysis or Conservative Treatment

What this Trial Is About

Researchers are studying the effects of physical activity in adults with chronic kidney disease CKD who are either on dialysis or receiving conservative treatment. The study aims to compare the impact of a combined high-intensity aerobic and strength training exercise program against a control group receiving usual care. This trial is sponsored by Casa di Cura Dott. Pederzoli and focuses on improving various health measures in CKD patients. Participants will be randomly assigned to one of two groups the exercise group will undergo a combined endurance and resistance training program three times a week for 24 weeks, while the control group will only participate in outcome measurements without exercise intervention. The exercise regimen involves both aerobic and strength exercises designed to assess physical function and capacity. During the study, participants will have regular assessments including physical performance tests, blood samples, body composition scans, and questionnaires evaluating quality of life and psychological status. These evaluations will be conducted over approximately one year to monitor gait speed, muscle strength, cardiopulmonary capacity, daily physical activity, nutritional status, vascular functions, and neuromuscular health. Safety and health status will be monitored throughout, with the study concluding by September 2026.

Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment