Actively Recruiting
Analysis of the Microenvironment of Lung Cancer and Exploration of the Mechanism of Resistance to Immunotherapy
Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2022-12-20
200
Participants Needed
1
Research Sites
573 weeks
Total Duration
On this page
Sponsors
T
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor
S
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators plan to conduct a multiomics analysis（such as, Genomics, proteomics, single cell RNA sequencing, space transcriptomics）of tumor tissue and blood, aiming at analyzing tumor heterogeneity, mapping the microenvironment map of lung cancer and exploring the mechanism of sensitivity and resistance to anti-PD1/PD-L1 antibodies.
CONDITIONS
Official Title
Analysis of the Microenvironment of Lung Cancer and Exploration of the Mechanism of Resistance to Immunotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathology or hemology diagnostics of lung cancer
- Patients have never received any antineoplastic therapy
You will not qualify if you...
- Other active malignancies within 5 years or at the same time
- Participation in interventional clinical research or use of research drugs/devices within 4 weeks before first treatment
- Active autoimmune diseases requiring systemic treatment within 2 years before first treatment
- Systemic glucocorticoid or immunosuppressive therapy within 7 days before first treatment (physiological dose glucocorticoids allowed)
- History of allogeneic organ or hematopoietic stem cell transplantation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Fourth Affiliated Hospital of Zhejiang University
Yiwu, Zhejiang, China, 310000
Actively Recruiting
Research Team
K
Kai Wang, PhD
CONTACT
J
Jiangnan Zhao, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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