Actively Recruiting
Analysis of Ocular Surface Microbiota in Dry Eye Patients After Femtosecond Laser-assisted In-situ Keratomileusis (FS-LASIK)
Led by Second Affiliated Hospital of Nanchang University · Updated on 2024-07-31
200
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
By using 16S rRNA sequencing technology to analyze the changes in ocular surface microbiota before and after surgery, as well as the impact of changes in ocular surface microbiota on FS-LASIK induced DES, new treatment ideas are provided for corneal FS-LASIK induced DES patients, and the incidence of FS-LASIK related DES is reduced.
CONDITIONS
Official Title
Analysis of Ocular Surface Microbiota in Dry Eye Patients After Femtosecond Laser-assisted In-situ Keratomileusis (FS-LASIK)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Stable refractive index with less than 0.5 diopters change in the past 2 years
- Best corrected distance vision (CDVA) of 1.0 or better
- For postoperative dry eye patients: Eye Surface Disease Index (OSDI) of 13 or higher plus at least two of the following: Tear film breakup time (BUT) 10 seconds or less, Schirmer I test 10 mm/5 min or less, corneal fluorescein staining with more than 5 spots
You will not qualify if you...
- History of eye trauma or surgery
- Suspected keratoconus
- Previous diagnosis of other eye diseases such as keratitis, edema, glaucoma, uveitis, retinal detachment, macular degeneration, cataracts, amblyopia
- History of severe dry eye disease before surgery
- Presence of systemic diseases like hyperthyroidism or autoimmune diseases
- Severe mental disorders such as anxiety or depression
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Yifeng Yu
Nanchang, Jiangxi, China, 330008
Actively Recruiting
Research Team
Y
yifeng yu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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