Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05945524

Analysis of the Resistance and Sensitivity Mechanisms to Teclistamab by Focusing on Single Immune Cell Examination

Led by University Hospital, Toulouse · Updated on 2025-04-10

100

Participants Needed

18

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to discover the immune and oncogenomic features that distinguish patients who respond to teclistamab from patients who are primarily resistant. Moreover, phenotypic and genotypic characteristics that occur with secondary resistance to teclistamab will be analyzed.

CONDITIONS

Official Title

Analysis of the Resistance and Sensitivity Mechanisms to Teclistamab by Focusing on Single Immune Cell Examination

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with multiple myeloma
  • Receiving teclistamab treatment
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Under legal protection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 18 locations

1

CHU d'Amiens

Amiens, France, France, 80054

Actively Recruiting

2

CHU de Caen

Caen, France, France, 14033

Actively Recruiting

3

Polyclinique du Parc Drevon

Dijon, France, France, 21000

Actively Recruiting

4

CH Annecy Genevois

Epagny Metz- Tessy, France, France, 74370

Actively Recruiting

5

CHU de Lille

Lille, France, France, 59037

Actively Recruiting

6

Centre Léon Bérard

Lyon, France, France, 69373

Actively Recruiting

7

CHU de Montpellier

Montpellier, France, France, 34295

Actively Recruiting

8

Hôpital Saint-Louis

Paris, France, France, 75010

Actively Recruiting

9

Hôpital Saint-Antoine

Paris, France, France, 75012

Actively Recruiting

10

Hôpital Necker

Paris, France, France, 75015

Actively Recruiting

11

CHU de Bordeaux

Pessac, France, France, 33600

Actively Recruiting

12

CHU de Lyon

Pierre-Bénite, France, France, 69495

Actively Recruiting

13

CHU de Poitiers

Poitiers, France, France, 86021

Actively Recruiting

14

CHU de Rennes

Rennes, France, France, 35033

Actively Recruiting

15

CH Saint-Etienne

Saint-Priest-en-Jarez, France, France, 42271

Actively Recruiting

16

CHU de Toulouse

Toulouse, France, France, 31059

Actively Recruiting

17

CHU de Tours

Tours, France, France, 37044

Actively Recruiting

18

CHRU Nancy

Vandœuvre-lès-Nancy, France, France, 54500

Actively Recruiting

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Research Team

H

Hervé AVET LOISEAU, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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