Actively Recruiting
Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients
Led by First Affiliated Hospital of Chongqing Medical University · Updated on 2025-02-14
65
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to analyze risk factors for high intraocular pressure and retinal detachment recurrence in patients with rhegmatogenous retinal detachment. It is a retrospective observational study including patients who visited the ophthalmology clinic of the First Affiliated Hospital of Chongqing Medical University between September 1, 2024, and December 31, 2025. The study will collect clinical data after obtaining informed consent to better understand these complications following surgery. The surgical procedure studied involves vitrectomy combined with retinal laser photocoagulation, retinal reattachment, and silicone oil tamponade. Some patients may also receive cataract extraction and intraocular lens implantation if needed. Patients will be observed at specific times after surgery: 1 day, 1 week, 1 month, 3 months, 6 months, and before silicone oil removal to assess outcomes. Participants will undergo measurements of intraocular pressure and retinal recovery status at these follow-up visits. Researchers will record any events that occur during the trial and provide treatment as necessary. The collected data will be statistically analyzed to identify factors linked to increased eye pressure and retinal detachment coming back. The study spans the surgery and postoperative follow-up period, aiming to improve understanding of these eye conditions.
CONDITIONS
Brief Title
Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with rhegmatogenous retinal detachment
- Aged over 18 years old
- Normal mental and psychological status
- Intraocular pressure less than 21 mmHg in both eyes before surgery
- No personal or family history of glaucoma
- Cup-to-disc ratio less than 0.5 in both eyes
- Understands the study purpose and signs informed consent
- High degree of compliance with study requirements
You will not qualify if you...
- High intraocular pressure before surgery
- Ophthalmic diseases such as glaucoma
- Acute or chronic systemic infections
- Hematological diseases
- History of mental and psychological diseases
- Incomplete survey data or inability to cooperate
- Traumatic rhegmatogenous retinal detachment
- Active ocular infectious lesions in either eye
- Severe refractive media opacity affecting imaging
- History of congenital structural abnormalities in the target eye
- Previous vitrectomy for other vitreoretinal diseases in the target eye
- Considered unfit by researchers to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo vitrectomy with silicone oil tamponade surgery and initial post-operative assessments.
1 visit (in-person)
Duration - 6 months
Participants are monitored to measure intraocular pressure and retinal recovery status at multiple time points after surgery.
Visits at 1 day, 1 week, 1 month, 3 months, 6 months postoperatively, and before silicone oil removal
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400042
Actively Recruiting
Research Team
H
Hui Peng
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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