Actively Recruiting
Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-04-24
40
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
F
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Sponsor
U
University of Bergen
Collaborating Sponsor
AI-Summary
What this Trial Is About
Studying genetic predisposition in autoimmune neurological diseases could help improve diagnostic accuracy and offer new treatment possibilities
CONDITIONS
Official Title
Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults diagnosed with NMOSD associated with AQP4 autoantibodies meeting 2015 diagnostic criteria and having at least one autoimmune comorbidity
- Adults diagnosed with myasthenia gravis associated with AChR autoantibodies and at least one autoimmune comorbidity
- Adults diagnosed with autoimmune encephalitis positive for LGI1 and CASPR2 autoantibodies and with at least one autoimmune comorbidity
- Adults with dominant pathogenic or homozygous AIRE mutations
You will not qualify if you...
- Presence of untreated thymoma
- History of thymoma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione Policlinico Universitario Agostino Gemelli, IRCSS Roma
Roma, Italy, 00136
Actively Recruiting
Research Team
R
Raffaele Iorio, MD
CONTACT
M
Martina Marini, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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