Actively Recruiting

Phase Not Applicable
Age: 30Years +
All Genders
Healthy Volunteers
NCT06993558

Analysis of Safety and Tissue Interaction of Injectable and Energy-based Biosmulators

Led by Universitätsklinikum Hamburg-Eppendorf · Updated on 2025-05-29

90

Participants Needed

1

Research Sites

78 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this clinical trial is to analyse tissue changes in the pre-auricular region after injectable (Poly-L-Lactic-Acid/Calcium-Hydroxylapatit/ and energy-based (Radiofrequency Microneedling) biostimulatory interventions in healthy volunteers. The main questions it aims to answer are: How is the Safety Profile of Biostimulatory Treatments? How are the Tissue Interactions after Biostiomulatory Treatments? Participants will: * Recieve one of 3 possible biostumulatory treatments (PLLA/CAHA/RFM) * Attend 5 follow-up appointments after treatment for checkups, surveillance and examinations.

CONDITIONS

Official Title

Analysis of Safety and Tissue Interaction of Injectable and Energy-based Biosmulators

Who Can Participate

Age: 30Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 30 years and older
  • Good general health with no relevant pre-existing conditions
  • Planning to undergo CaHA, PLLA, or RFMN treatment for skin laxity or volume loss
  • Able to give informed consent
  • Willing and able to attend follow-up visits
Not Eligible

You will not qualify if you...

  • Under 30 years of age
  • Pregnant or breastfeeding
  • Significant open wounds or lesions in treatment area
  • Metallic implants in the treatment area
  • Psychiatric disorders such as psychosis or body dysmorphic disorder
  • Missing informed consent or data privacy declarations

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Hamburg Eppendorf

Hamburg, Free and Hanseatic City of Hamburg, Germany, 20246

Actively Recruiting

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Research Team

L

Lynhda Nguyen, M.D.

CONTACT

K

Katarina Herberger, MD. PHD.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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