Actively Recruiting

Age: 18Years +
All Genders
ID06552910

Diabetic Foot Amputations: A Comprehensive Review of Anesthetic Procedures and Outcomes

Led by Ankara City Hospital Bilkent · Updated on 2024-09-05

450

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Diabetic foot is a serious complication of diabetes that can lead to ulceration, infection, bone damage, and gangrene, often requiring surgical treatment such as amputation or debridement. This research evaluates the impact of different anesthetic methods, specifically peripheral nerve block (PNB) versus general anesthesia, on outcomes after diabetic foot amputation. The study focuses on inpatient data collected retrospectively from 2021 to 2023 to determine if PNB results in fewer postoperative complications and better recovery. Patients who had amputations of the toe, ankle, or foot under different anesthesia types were included. The study compares PNB, which involves injecting anesthetic near specific nerves under ultrasound guidance, with general anesthesia and other regional anesthetics. Data collected includes patient demographics, preoperative medications, comorbid conditions, surgical details, and anesthesia types. The study reviews major complications such as pneumonia, heart attack, stroke, kidney injury, infections, and re-operations. Outcomes also include mortality within 30 days and the length of hospital stay. Participants' medical records are analyzed for demographic and clinical characteristics, medication use, comorbidities, surgical details, and complications. Statistical methods will assess associations between anesthesia and postoperative outcomes, including survival analysis for hospital stay duration and logistic regression adjusting for confounding factors. The primary measure is 30-day mortality after surgery, with secondary measures of morbidity and hospital discharge timing. This retrospective review is based on existing patient data without altering treatment during the study period.

CONDITIONS

Brief Title

Analyzing Anesthetic Techniques in Diabetic Foot Amputation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with diabetic foot requiring amputation
  • Patients who underwent toe, ankle, or foot amputation
  • Patients aged 18 years or older
Not Eligible

You will not qualify if you...

  • Patients under the age of 18
  • Amputations performed for reasons other than diabetic foot
  • Patients with incomplete or insufficient medical records

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Day of surgery

Participants undergo diabetic foot amputation surgery with anesthesia administered via peripheral nerve block. Immediate post-operative care includes monitoring and managing surgical outcomes and complications.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - Up to 3 months after surgery

Participants are monitored for post-surgical complications, recovery progress, and hospital discharge. Outcomes such as morbidity and mortality are assessed during this period.

Visits as needed until hospital discharge

Trial Site Locations

Total: 1 location

1

Semih Başkan

Etimesgut, Ankara, Turkey (Türkiye), 06790

Actively Recruiting

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Research Team

S

Semih Başkan, MD

S

Semih Başkan

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Effect of peripheral nerve block versus general anesthesia on the hemodynamics and prognosis of diabetic patients undergoing diabetic foot Surgery.

Gehua Zhu, Jiamin Xu, Hanying Dai...

https://pubmed.ncbi.nlm.nih.gov/37880794

Effects of Anesthetic Techniques on the Risk of Postoperative Complications Following Lower Extremity Amputation in Diabetes Patients with Coagulation Abnormalities: A Retrospective Cohort Study Using Propensity Score Analysis.

Hye Jin Kim, Chun-Gon Park, Yong Seon Choi...

https://pubmed.ncbi.nlm.nih.gov/34884298