Amputation in diabetic foot ulcer: A treatment dilemma.
Raden Andri Primadhi, Rani Septrina, Putie Hapsari...
https://pubmed.ncbi.nlm.nih.gov/37304194Actively Recruiting
Led by Ankara City Hospital Bilkent · Updated on 2024-09-05
450
Participants Needed
1
Research Sites
4 weeks
Total Duration
Diabetic foot is a serious complication of diabetes that can lead to ulceration, infection, bone damage, and gangrene, often requiring surgical treatment such as amputation or debridement. This research evaluates the impact of different anesthetic methods, specifically peripheral nerve block (PNB) versus general anesthesia, on outcomes after diabetic foot amputation. The study focuses on inpatient data collected retrospectively from 2021 to 2023 to determine if PNB results in fewer postoperative complications and better recovery. Patients who had amputations of the toe, ankle, or foot under different anesthesia types were included. The study compares PNB, which involves injecting anesthetic near specific nerves under ultrasound guidance, with general anesthesia and other regional anesthetics. Data collected includes patient demographics, preoperative medications, comorbid conditions, surgical details, and anesthesia types. The study reviews major complications such as pneumonia, heart attack, stroke, kidney injury, infections, and re-operations. Outcomes also include mortality within 30 days and the length of hospital stay. Participants' medical records are analyzed for demographic and clinical characteristics, medication use, comorbidities, surgical details, and complications. Statistical methods will assess associations between anesthesia and postoperative outcomes, including survival analysis for hospital stay duration and logistic regression adjusting for confounding factors. The primary measure is 30-day mortality after surgery, with secondary measures of morbidity and hospital discharge timing. This retrospective review is based on existing patient data without altering treatment during the study period.
CONDITIONS
Analyzing Anesthetic Techniques in Diabetic Foot Amputation
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo diabetic foot amputation surgery with anesthesia administered via peripheral nerve block. Immediate post-operative care includes monitoring and managing surgical outcomes and complications.
1 surgical visit (in-person)
Duration - Up to 3 months after surgery
Participants are monitored for post-surgical complications, recovery progress, and hospital discharge. Outcomes such as morbidity and mortality are assessed during this period.
Visits as needed until hospital discharge
Total: 1 location
1
Semih Başkan
Etimesgut, Ankara, Turkey (Türkiye), 06790
Actively Recruiting
S
Semih Başkan, MD
S
Semih Başkan
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Raden Andri Primadhi, Rani Septrina, Putie Hapsari...
https://pubmed.ncbi.nlm.nih.gov/37304194Gehua Zhu, Jiamin Xu, Hanying Dai...
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https://pubmed.ncbi.nlm.nih.gov/34884298