Actively Recruiting
Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis A Randomized Prospective Study
Led by La Tour Hospital · Updated on 2026-05-22
296
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the functional outcomes of two types of shoulder replacement surgeries—anatomic total shoulder arthroplasty (TSA) and reverse total shoulder arthroplasty (RTSA)—for patients with primary glenohumeral osteoarthritis who have intact rotator cuffs and no significant glenoid retroversion. The study aims to determine if RTSA provides at least as good results as anatomic TSA and also to explore whether RTSA might lead to better clinical and radiographic outcomes with fewer complications. Participants will be randomly assigned to receive either an anatomic TSA or an RTSA through a deltopectoral surgical approach. Both procedures involve implanting a prosthesis designed to treat primary glenohumeral arthritis. The study compares these two surgical options over a follow-up period of two years. During the study, patients will be assessed using several measures including the American Shoulder and Elbow Surgeons (ASES) score, Subjective Shoulder Value (SSV), range of motion, pain on a visual analog scale, Constant score, and Short Form-12 (SF-12). Radiographic evaluations and complication rates will also be recorded over the two-year postoperative period. The total participation duration includes baseline assessment and follow-up evaluations spanning up to two years after surgery.
CONDITIONS
Brief Title
Anatomic TSA vs RTSA for Glenohumeral Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Primary glenohumeral arthritis
- Intact rotator cuff
- No significant glenoid bone loss
- Age between 65 and 85 years
- Signed informed consent
You will not qualify if you...
- B2 glenoid with more than 80% posterior humeral head subluxation or greater than 25 degrees neoglenoid retroversion
- B3 and C type glenoids
- Full thickness rotator cuff tear
- Acute or malunited proximal humeral fracture
- Chronic locked dislocation
- Rheumatoid arthritis
- Revision surgery or previous shoulder surgery
- Tumors
- Axillary nerve damage
- Non-functioning deltoid muscle
- Glenoid vault deficiency preventing baseplate fixation
- Infection and neuropathic joints
- Known or suspected non-compliance, drug or alcohol abuse
- Incapable of judgement or under legal guardianship
- Inability to follow study procedures due to language, psychological disorders, dementia, or contraindication for CT scan
- Investigator or related persons enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery plus immediate recovery period
Participants receive either an anatomic total shoulder arthroplasty (TSA) or a reverse total shoulder arthroplasty (RTSA) to treat primary glenohumeral arthritis through a deltopectoral approach.
1 surgery visit and immediate post-operative assessments
Duration - 2 years
Participants are monitored for clinical outcomes, shoulder function, pain, complications, and radiographic changes for up to 2 years following surgery.
Regular follow-up visits during the 2 years postoperative period
Trial Site Locations
Total: 1 location
1
La Tour Hospital
Meyrin, Switzerland, 1217
Actively Recruiting
Research Team
A
Alexandre Lädermann, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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