Actively Recruiting
Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD
Led by Seung-Whan Lee, M.D., Ph.D. · Updated on 2025-01-10
2400
Participants Needed
17
Research Sites
385 weeks
Total Duration
On this page
Sponsors
S
Seung-Whan Lee, M.D., Ph.D.
Lead Sponsor
B
Biotronik Korea Co., Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is to compare clinical outcomes between quantitative coronary angiography-guided anatomic complete revascularization and fractional flow reserve-guided physiologic complete revascularization in patients with significant coronary artery disease undergoing percutaneous coronary intervention with drug eluting stent
CONDITIONS
Official Title
Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men or women aged 19 years or older
- Typical chest pain or objective evidence of myocardial ischemia suitable for PCI
- Significant coronary lesions with diameter stenosis of 50-90% in major epicardial arteries 65 2.25 mm in diameter
- Patient or guardian agrees to study protocol, follow-up schedule, and provides written informed consent
You will not qualify if you...
- Coronary lesions making FFR measurement not possible (e.g., severe vessel tortuosity or angulation)
- Chronic total occlusion
- Failed PCI of severe stenotic or acute coronary syndrome culprit lesions
- PCI within 6 months before the index procedure
- Prior coronary artery bypass graft surgery
- Cardiogenic shock or hemodynamic instability
- Left ventricular ejection fraction less than 35%
- Life expectancy less than 1 year due to any cause
- Planned surgery requiring general anesthesia or stopping aspirin/ADP antagonists within 12 months after procedure
- Cancer diagnosis within past 3 years or current active cancer treatment (except superficial skin cancers)
- Pregnant, breastfeeding, or of child-bearing potential
- Known intolerance to antiplatelet agents (aspirin, clopidogrel, prasugrel, ticagrelor)
- Hypersensitivity or contraindication to drug-eluting stent materials
- Any significant abnormality at screening that would prevent safe study completion
- Unwillingness or inability to comply with study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 17 locations
1
Hallym University Sacred Heart Hospital
Anyang, South Korea
Not Yet Recruiting
2
Bucheon Sejong Hospital
Bucheon-si, South Korea
Not Yet Recruiting
3
Inje University Busan Paik Hospital
Busan, South Korea
Actively Recruiting
4
Gyeongsang National University Changwon Hospital
Changwon, South Korea
Actively Recruiting
5
Chungbuk National University Hospital
Cheongju-si, South Korea
Actively Recruiting
6
Daegu Veterans Hospital
Daegu, South Korea
Actively Recruiting
7
Keimyung University Dongsan Medical Center
Daegu, South Korea
Actively Recruiting
8
Gangneung Asan Hospital
Gangneung, South Korea
Actively Recruiting
9
Wonkwang University Hospital
Iksan, South Korea
Actively Recruiting
10
Kwangju Christian Hospital
Kwangju, South Korea
Actively Recruiting
11
Inje University Pusan Paik Hospital
Pusan, South Korea
Actively Recruiting
12
Bundang CHA Hospital
Seongnam, South Korea
Not Yet Recruiting
13
Asan Medical Center
Seoul, South Korea
Actively Recruiting
14
Korea University Anam Hospital
Seoul, South Korea
Actively Recruiting
15
Veterans Hospital Service Medical Center
Seoul, South Korea
Actively Recruiting
16
The Catholic University of Korea, ST. Vincent's Hospital
Suwon, South Korea
Not Yet Recruiting
17
Pusan National University Yangsan Hospital
Yangsan, South Korea
Not Yet Recruiting
Research Team
J
Jiwon Baek, RN
CONTACT
S
Seung-Whan Lee, Investigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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