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Age: 40Years - 80Years
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ID07179029

Study of Myocardial Injury Caused by Anesthesia in Adults Aged 40 to 80 Undergoing Non-Heart Surgery

Led by University Hospital Tuebingen · Updated on 2025-09-17

3000

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

This research investigates myocardial injury occurring during non-cardiac surgery, a condition known to affect up to 16% of high-risk patients and pose significant challenges to healthcare. The study focuses on perioperative myocardial injury, characterized by elevated cardiac troponin levels without full myocardial infarction criteria, and aims to understand anesthesia-related and surgical risk factors for this condition. Identifying these factors is important for improving preoperative care and guiding future interventional studies. The study is observational and will include patients undergoing elective or emergency non-cardiac surgeries. Researchers will observe variables such as anesthesia methods, hemodynamics, medications used, and surgical duration, which may influence myocardial injury risk. The investigation will not involve specific treatments but will monitor these factors during the perioperative period. Participants will be adults aged 40 to 80 years with at least two cardiovascular risk factors, undergoing surgery classified as ASA II to IV. The study will track cardiac troponin levels and the incidence of perioperative myocardial injury within the first five days after surgery. Mortality will also be monitored for up to 30 days. Data collection includes clinical assessments and follow-up to better understand risk and outcomes associated with myocardial injury after surgery.

CONDITIONS

Brief Title

Anesthesia Induced Myocardial Injury in Non-cardiac Surgery (AIMY)

Research Team

M

Michael Koeppen, MD

S

Sibel Sari-Yavuz, MD

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