Actively Recruiting
Anesthesia Induced Myocardial Injury in Non-cardiac Surgery (AIMY)
Led by University Hospital Tuebingen · Updated on 2025-09-17
3000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research investigates myocardial injury occurring during non-cardiac surgery, a condition known to affect up to 16% of high-risk patients and pose significant challenges to healthcare. The study focuses on perioperative myocardial injury, characterized by elevated cardiac troponin levels without full myocardial infarction criteria, and aims to understand anesthesia-related and surgical risk factors for this condition. Identifying these factors is important for improving preoperative care and guiding future interventional studies. The study is observational and will include patients undergoing elective or emergency non-cardiac surgeries. Researchers will observe variables such as anesthesia methods, hemodynamics, medications used, and surgical duration, which may influence myocardial injury risk. The investigation will not involve specific treatments but will monitor these factors during the perioperative period. Participants will be adults aged 40 to 80 years with at least two cardiovascular risk factors, undergoing surgery classified as ASA II to IV. The study will track cardiac troponin levels and the incidence of perioperative myocardial injury within the first five days after surgery. Mortality will also be monitored for up to 30 days. Data collection includes clinical assessments and follow-up to better understand risk and outcomes associated with myocardial injury after surgery.
CONDITIONS
Brief Title
Anesthesia Induced Myocardial Injury in Non-cardiac Surgery (AIMY)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 40 to 80 years
- Undergoing elective or emergency non-cardiac surgery
- Have at least two cardiovascular risk factors, such as age over 60, hypertension, diabetes, coronary heart disease, peripheral arterial disease, cerebrovascular disease, chronic kidney problems, heart failure, chronic lung disease, or active smoking
- ASA classification II to IV
- Able to provide written informed consent after explanation
You will not qualify if you...
- Unable to provide consent due to sedation or intubation
- Undergoing cardiac surgery, obstetric procedures, or minor surgeries not requiring general or regional anesthesia
- Having fewer than two cardiovascular risk factors
- Age under 40 or over 80 years
- ASA classification I
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 to 5 days
Participants undergo assessments related to non-cardiac surgery to evaluate anesthesia-induced myocardial injury.
1 to 5 visits during hospitalization
Duration - Up to 30 days
Participants are monitored for mortality and other outcomes following surgery.
Follow-up contacts up to 30 days after surgery
Trial Site Locations
Total: 1 location
1
University Clinic of Tuebingen
Tübingen, Germany
Actively Recruiting
Research Team
M
Michael Koeppen, MD
S
Sibel Sari-Yavuz, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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