Monitoring Sedation and Pain Response Using EEG During Painless Gastrointestinal Endoscopy A Clinical Study of qCON and qNOX Indices in Gastroscopy and Colonoscopy Patients

What this Trial Is About

Researchers are studying how to best monitor sedation and pain response during painless gastrointestinal endoscopy using a new medical device that measures brain activity. This device records two indices, the quantitative consciousness qCON and quantitative nociceptive qNOX, which may reflect sedation depth and pain signals. The study aims to combine these measurements with visual and physiological monitoring to find the optimal sedation level during gastroscopy and colonoscopy procedures. This single-center, prospective observational study involves 220 patients, evenly split between gastroscopy and colonoscopy groups. Patients receive anesthesia induction with propofol and sufentanil, monitored by an EEG bispectral index device Apollo-9000A to track qCON and qNOX values. The sedation is adjusted to keep patients at a low alertness level with no body movements during the procedures. Clinical signs like cough reflex and vital signs are also recorded. Participants will be observed throughout the procedure with measurements of qCON, qNOX, blood pressure, heart rate, oxygen saturation, and sedation scores. Adverse events during and up to 24 hours after the procedure will be documented. The main outcome is anesthesia quality during the procedure, with secondary outcomes including changes in monitoring indices and safety measures. The total study period covers the procedure and 24-hour follow-up for complications.

Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring