Actively Recruiting
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Led by Min Su · Updated on 2025-03-06
220
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious stimulation response has emerged. Its fundamental principle is based on the monitoring of electroencephalographic (EEG) activity, incorporating two monitoring parameters: the quantitative consciousness (qCON) index and the quantitative nociceptive (qNOX) index. However, in the context of sedation for gastrointestinal endoscopy, how the dynamic changes of the quantitative consciousness index (qCON) and the quantitative nociception index (qNOX) reflect the depth of sedation and nociceptive response remains unclear. Safe and effective sedation monitoring includes both direct visual monitoring and physiological monitoring, that is, monitoring the patient's hemodynamics and depth of sedation. This study utilizes qCON and qNOX monitoring to assess the sedation and analgesic states of patients undergoing painless gastroenterological endoscopy. By combining visual assessment (cough reflex, respiratory depression, and limb movement) with clinical physiological monitoring (vital signs monitoring and pulse oximetry), the aim is to explore the optimal sedation range for gastrointestinal endoscopy under sedation, providing new anesthesia monitoring tools for clinical use.
CONDITIONS
Official Title
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18-60 years old
- American Society of Anesthesiologists (ASA) Class I-III
- Body mass index (BMI) between 18 and 30 kg/m2
- Scheduled for elective gastroscopy or colonoscopy
- Willing to follow study procedures and sign informed consent
You will not qualify if you...
- Pregnant or breastfeeding women
- Allergy to sedatives/anesthetic drugs or severe anesthetic risks
- Chronic preoperative pain or history of substance abuse
- Severe neurological diseases such as stroke, hemiplegia, seizures, or epilepsy
- Difficult airway conditions like limited mouth opening or neck/jaw mobility issues
- Respiratory diseases including bronchitis, asthma, COPD, or acute respiratory infections
- Chronic pharyngitis, laryngitis, laryngeal edema, or recurrent laryngeal nerve paralysis
- Esophagitis, esophageal strictures, or motility disorders causing swallowing difficulty or reflux
- Poorly controlled life-threatening cardiovascular diseases such as severe hypertension or unstable angina
- Liver dysfunction (Child-Pugh grade C or above), acute upper gastrointestinal bleeding with shock, severe anemia, or gastrointestinal obstruction with retained gastric contents
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
China,Chongqing The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400016
Actively Recruiting
Research Team
Q
Qin Liu
CONTACT
S
Su Min
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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