Actively Recruiting
Anesthesia and Non-small Cell Lung Cancer Recurrence
Led by Samsung Medical Center · Updated on 2026-04-20
5384
Participants Needed
1
Research Sites
229 weeks
Total Duration
On this page
Sponsors
S
Samsung Medical Center
Lead Sponsor
S
Seoul National University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
There has been ongoing debate about the relationship between cancer recurrence and anesthetic management. Therefore, the investigators will test the hypothesis that the recurrence free survival (RFS) after curative resection of NSCLC is higher in patient who received total intravenous anesthesia (TIVA) than volatile anesthetics in this multi-center randomized trials.
CONDITIONS
Official Title
Anesthesia and Non-small Cell Lung Cancer Recurrence
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 19 years or older
- American Society of Anesthesiologists physical status (ASA) I to III
- Eastern Cooperative Oncology Group (ECOG) performance status 0 to 2
- Scheduled for lung resection surgery (segmentectomy, lobectomy, bilobectomy, pneumonectomy) with curative intent for NSCLC at clinical Tumor, Node, Metastasis (TNM) stage I to IIA
You will not qualify if you...
- Presence of distant metastasis or malignant tumor in other organs not in long-term remission
- Severe neurological conditions
- Severe liver disease classified as Child-Pugh C
- Renal failure requiring renal replacement therapy
- Anesthesia and/or surgery within the past year
- Previous lung cancer surgery except diagnostic biopsies
- Allergies or contraindications to study medications
- Planned combined extrapulmonary surgical procedures
- Surgery involving cardiopulmonary bypass or extracorporeal membrane oxygenation
- Postoperative sedation
- Pregnancy or breastfeeding
- Patient refusal to participate
AI-Screening
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Trial Site Locations
Total: 1 location
1
Samsung Medical Center
Seoul, Seoul-teukbyeolsi, South Korea, 06351
Actively Recruiting
Research Team
J
Jeayoun Kim, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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