Actively Recruiting
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
Led by Second Affiliated Hospital of Wenzhou Medical University · Updated on 2024-11-08
1860
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor
Z
Zhejiang Provincial People's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Anesthesia and perioperative Neurocognitive Disorders in the Elderly patients undergoing hip fracture Surgery platform trial (ANDES platform trial): A pragmatic multi-arm, adaptive, open label, multicenter randomized controlled platform trial to assess the effect of different enhance anesthesia technique in perioperative neurocognitive function, as compared to standard anesthesia care in the elderly patients undergoing hip fracture
CONDITIONS
Official Title
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 65 years and older.
- Patients with unilateral hip fracture (including femoral neck, femoral head, intertrochanteric and subtrochanteric fractures) are scheduled for surgical treatment.
- American Society of Anesthesiologists (ASA) physical status IV or below.
- The patients or family members provide written informed consent.
- Additional inclusion criteria may pertain to specific interventions and will be described in relevant sub-protocols.
You will not qualify if you...
- Patients with multiple trauma or fractures (excluding trauma judged by the researcher not to affect overall recovery, such as simple spinal compression fractures, mild soft tissue contusions, fractures of hands and feet).
- Two or more anesthetic surgeries are required.
- Patients with an obvious history of head trauma (such as loss of consciousness for more than 5 minutes, post-traumatic amnesia).
- Patients unable to complete the assessment of the primary outcome.
- Additional exclusion criteria may pertain to specific interventions and will be described in relevant sub-protocols.
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Second Affilliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China, 325000
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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