Actively Recruiting
Anorectal Manometery in Pediatric Chronic Refractory Constipation
Led by Ain Shams University · Updated on 2024-10-09
60
Participants Needed
1
Research Sites
55 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many institutions. In high resolution anorectal manometery we are able to gain information whether the symptoms are related to sphincter dysfunction, impaired sensation, or pelvic floor dyssynergia
CONDITIONS
Official Title
Anorectal Manometery in Pediatric Chronic Refractory Constipation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents aged 4 to 16 years
- Participants meeting Rome IV criteria for functional constipation, including at least 2 of: 2 or fewer bowel movements per week, at least 1 episode of fecal incontinence weekly, retentive posturing or stool retention, painful or hard bowel movements, large fecal mass in rectum, or large stools that may block toilet
- Symptoms not explained by other medical conditions
- Chronic refractory constipation defined as inability to pass stools despite maximum laxative therapy and requiring daily rectal stimulation
- Willing and able to keep a diary and complete questionnaires
- Informed consent signed by participant or legal representative
You will not qualify if you...
- Anorectal malformation
- Neurological disease affecting lower limbs
- History of hypersensitivity or allergies to lubiprostone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ain shams university
Cairo, Egypt
Actively Recruiting
Research Team
A
asmaa abdelnaby mohamed soliman, master
CONTACT
Y
yosra mohamed mohsen awad, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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