Study Comparing Two Types of Gastrojejunostomy After Pancreaticoduodenectomy to Reduce Delayed Gastric Emptying

What this Trial Is About

This research aims to compare the frequency of delayed gastric emptying DGE in patients undergoing a specific type of surgery called pancreaticoduodenectomy. It focuses on two different methods of reconnecting the stomach to the small intestine, called antecolic and retrocolic gastrojejunostomy. The study will help determine if one method leads to less delayed gastric emptying after surgery. Participants will undergo a pylorus-preserving pancreaticoduodenectomy and will be randomly assigned to receive either the antecolic gastrojejunostomy, where the connection is made in front of the transverse colon, or the retrocolic gastrojejunostomy, where the connection passes through the transverse mesocolon. The trial compares these two surgical techniques to evaluate their impact on delayed gastric emptying. During the three-year study period, researchers will monitor participants for the occurrence of delayed gastric emptying. They will collect data about the surgical outcomes and recovery. The study involves regular clinical assessments to evaluate the primary outcome, which is delayed gastric emptying, helping to understand which surgical method may influence this condition after pancreaticoduodenectomy.

Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure