Actively Recruiting
Antecolic Versus Retrocolic Gastrojejunostomy Following Pancreaticoduodenectomy: A Prospective Randomised Study
Led by University of Thessaly · Updated on 2025-06-06
76
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare the frequency of delayed gastric emptying (DGE) in patients undergoing a specific type of surgery called pancreaticoduodenectomy. It focuses on two different methods of reconnecting the stomach to the small intestine, called antecolic and retrocolic gastrojejunostomy. The study will help determine if one method leads to less delayed gastric emptying after surgery. Participants will undergo a pylorus-preserving pancreaticoduodenectomy and will be randomly assigned to receive either the antecolic gastrojejunostomy, where the connection is made in front of the transverse colon, or the retrocolic gastrojejunostomy, where the connection passes through the transverse mesocolon. The trial compares these two surgical techniques to evaluate their impact on delayed gastric emptying. During the three-year study period, researchers will monitor participants for the occurrence of delayed gastric emptying. They will collect data about the surgical outcomes and recovery. The study involves regular clinical assessments to evaluate the primary outcome, which is delayed gastric emptying, helping to understand which surgical method may influence this condition after pancreaticoduodenectomy.
CONDITIONS
Brief Title
Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years old
- Scheduled for elective pancreaticoduodenectomy
- Signed consent form
You will not qualify if you...
- Age under 18 years old
- Participation in other clinical trials that may affect study results
- Do not consent to participate in the study
AI-Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospital discharge
Participants undergo pancreaticoduodenectomy with either antecolic or retrocolic gastrojejunostomy as part of the procedure.
1 surgery and immediate in-hospital care period
Duration - Up to 3 years
Participants are monitored for recovery and potential delayed gastric emptying following surgery.
Follow-up visits as scheduled by the clinical team
Trial Site Locations
Total: 1 location
1
University of Thessaly
Larissa, Greece, 41500
Actively Recruiting
Research Team
C
Chrysoula C Kolla
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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