Actively Recruiting
Antegrade Autologous Blood Reinfusion After CPB
Led by Kocaeli City Hospital · Updated on 2026-02-24
130
Participants Needed
1
Research Sites
16 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective observational study aims to evaluate the effect of antegrade pump blood reinfusion using the crystalloid "chase" technique on postoperative transfusion requirements in adult patients undergoing cardiac surgery with cardiopulmonary bypass. At the end of cardiopulmonary bypass, blood remaining within the cardiopulmonary bypass circuit is reinfused antegradely through the arterial line using a crystalloid chase, without collection or storage. Blood remaining within the bypass circuit after surgery represents a valuable source of autologous blood, and its reinfusion may contribute to perioperative blood conservation strategies. Patients receiving antegrade pump blood reinfusion via the chase technique will be compared with those managed without reinfusion, without any intervention by the investigators. The primary outcome is postoperative blood transfusion requirement.
CONDITIONS
Official Title
Antegrade Autologous Blood Reinfusion After CPB
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 80 years
- Patients undergoing elective, isolated coronary artery bypass grafting surgery using cardiopulmonary bypass (on-pump).
You will not qualify if you...
- Emergency or Redo cardiac surgery
- Concomitant cardiac procedures such as valve repair or replacement, or aortic surgery
- Planned or intraoperative conversion to off-pump coronary artery bypass grafting
- Preoperative hematocrit less than 30% or known inherited/acquired bleeding disorders
- Preoperative left ventricular ejection fraction less than 30%
- Thrombocytopenia or abnormal coagulation tests
- Use of antiplatelet agents other than aspirin without proper preoperative discontinuation
- Use of anticoagulant therapy without proper preoperative discontinuation
- Use of non-steroidal anti-inflammatory drugs (NSAIDs) without proper discontinuation before surgery
- Severe renal dysfunction or dialysis
- Severe hepatic dysfunction or coagulopathy
- Active infection or systemic inflammatory or autoimmune disease
- Active malignancy requiring ongoing treatment
- Refusal or inability to provide written informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Kocaeli City Hospital
Kocaeli, Izmit, Turkey (Türkiye)
Actively Recruiting
Research Team
Y
Yılmaz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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