Actively Recruiting
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
Led by National University Hospital, Singapore · Updated on 2025-12-09
182
Participants Needed
1
Research Sites
195 weeks
Total Duration
On this page
Sponsors
N
National University Hospital, Singapore
Lead Sponsor
N
National University of Singapore
Collaborating Sponsor
AI-Summary
What this Trial Is About
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated by Type 2 Diabetes Mellitus (T2DM). It seeks to assess myo-inositol's potential to support fetal and neonatal health, and optimise maternity outcomes as a complementary approach and adjuvant to existing diabetes mellitus therapies, as well as investigate the underlying biological mechanisms.
CONDITIONS
Official Title
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant women aged 21 years to 45 years old at the time of recruitment
- Ongoing, viable, singleton intrauterine pregnancy
- Between 12+0 days and 16+6 days weeks' gestation at recruitment
- Diagnosed with Type 2 Diabetes Mellitus by documented 75g Oral Glucose Tolerance Test showing fasting glucose >7 mmol/L or 2-hour glucose >11.1 mmol/L, or HbA1C >6.5%, prior to pregnancy or during first 16 weeks of pregnancy
- Intend to receive antenatal care and give birth at NUH
- Willing to provide written, informed consent
- Able to swallow capsules and comply with trial procedures
You will not qualify if you...
- Known or suspected fetal aneuploidy or genetic/structural anomaly
- Severe allergy to food items requiring carriage of an Epipen at all times
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
National University Hospital
Singapore, Singapore, Singapore, 119228
Actively Recruiting
Research Team
G
Gladys Woon, Bsc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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